SubsidieMeestersSupramolecular microcapsules for bioreactor expansion of induced pluripotent stem cells
The SUPROTECT project aims to develop squaramide-based microcapsules for culturing pluripotent stem cells, evaluating their effectiveness while securing intellectual property for potential licensing.
Projectdetails
Introduction
The SUPROTECT proof-of-concept project seeks to apply our squaramide-based (SQ) supramolecular materials to prepare microcapsules for the culture of pluripotent stem cells.
Project Objectives
Building on earlier demonstrations of bioactive hydrogel synthesis and in vitro culture of iPSCs in 3D cell culture under static conditions, we will:
- Synthesize the necessary amount of material for iPSC culture studies.
- Develop protocols to prepare microcapsules with and without iPSCs.
- Evaluate the feasibility of the different microcapsules for the culture of iPSCs and their release, ranking the approaches based on iPSC number and quality for further downstream application.
Market Research
In parallel with these activities, we will perform detailed market research studies on microfabricated polymer materials for the culture of various cell types. This will help in:
- Protecting our intellectual property (IP) position.
- Consolidating our findings in a package for product licensing with the appropriate party.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-6-2024 |
| Einddatum | 30-11-2025 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- UNIVERSITEIT LEIDENpenvoerder
Land(en)
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This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
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This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
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PRInted Symbiotic Materials as a dynamic platform for Living Tissues production
PRISM-LT aims to develop a flexible bioprinting platform using hybrid living materials to enhance stem cell differentiation with engineered helper cells for biomedical and food applications.
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iNSIGHT aims to develop precision probiotics through innovative microencapsulation for targeted delivery, enhancing gut health and addressing related diseases using advanced technology and personalized treatment.
SBMP - disrupting the manufacturing of biological drugs through a ground-breaking nanotechnology-based microcarrier
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