SubsidieMeestersRevolutionary vascular repair patch to treat aortic dissections
Aortyx's biomimetic bioresorbable adhesive patch aims to treat aortic dissections via endovascular deployment, enhancing natural repair and reducing mortality compared to traditional stents.
Projectdetails
Introduction
Aortyx has developed a biomimetic bioresorbable adhesive patch to treat aortic dissections. It is inserted in the aorta through a femoral access using an endovascular catheter and a deployer.
Mechanism of Action
The patch adheres to the aortic tear, stopping false lumen blood flow, and promotes natural repair and biointegration thanks to its patented microstructure and viscoelasticity.
Current Challenges
Current endovascular approaches use rigid grafted stents that have multiple drawbacks with continuing high mortality rates.
Advantages of Our Solution
These approaches will be replaced by our viscoelastic biomimetic patch that has minimal side effects and promotes natural repair of the artery. Consequently, our device will:
- Reduce AD-associated mortality
- Improve post-intervention quality of life for patients
- Reduce post-operative stay
- Increase patient eligibility
Funding Request
We seek EIC Accelerator funding to fund the testing that will prove the scalability of our solution and set us on the path to becoming a global champion of aortic devices.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.500.000 |
| Totale projectbegroting | € 4.261.117 |
Tijdlijn
| Startdatum | 1-5-2022 |
| Einddatum | 31-1-2025 |
| Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- AORTYX SLpenvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
A minimally invasive and durable endograft fastening solution for Abdominal Aortic Aneurysm (AAA)Aortoseal is an innovative implant for endovascular aneurysm repair that combines the stability of open surgery with the safety of EVAR, aiming to improve patient outcomes and save healthcare costs. | EIC Accelerator | € 2.499.999 | 2023 | Details |
Next-generation heart bypass grafts to naturally restore cardiovascular function.Xeltis aims to clinically validate a restorative vascular graft (XABG) to treat coronary artery disease without vein harvesting, enhancing patient outcomes and reducing healthcare costs. | EIC Accelerator | € 2.481.701 | 2022 | Details |
Minimally invasive suturing for vascular bore closure and heart defect repairNovelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures. | EIC Accelerator | € 2.499.999 | 2024 | Details |
THE NEXT STENT GENERATION: A FIRST-IN-CLASS REGENERATIVE NANOFIBER STENT TO RECONSTRUCT ARTERIES FROM THE INSIDE OUTSTENTiT aims to revolutionize BTK-CLI treatment with a regenerative stent that promotes vascular restoration and reduces complications, seeking €2.5M in grants and €10M in equity for clinical studies. | EIC Accelerator | € 2.500.000 | 2023 | Details |
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A minimally invasive and durable endograft fastening solution for Abdominal Aortic Aneurysm (AAA)
Aortoseal is an innovative implant for endovascular aneurysm repair that combines the stability of open surgery with the safety of EVAR, aiming to improve patient outcomes and save healthcare costs.
Next-generation heart bypass grafts to naturally restore cardiovascular function.
Xeltis aims to clinically validate a restorative vascular graft (XABG) to treat coronary artery disease without vein harvesting, enhancing patient outcomes and reducing healthcare costs.
Minimally invasive suturing for vascular bore closure and heart defect repair
Novelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures.
THE NEXT STENT GENERATION: A FIRST-IN-CLASS REGENERATIVE NANOFIBER STENT TO RECONSTRUCT ARTERIES FROM THE INSIDE OUT
STENTiT aims to revolutionize BTK-CLI treatment with a regenerative stent that promotes vascular restoration and reduces complications, seeking €2.5M in grants and €10M in equity for clinical studies.
Medical nanofiber technology to prevent cerebrospinal leakage in neurosurgeries
Nurami's ArtiFix is a revolutionary bio-absorbable patch designed to prevent cerebrospinal fluid leaks post-surgery, improving patient outcomes and reducing healthcare costs.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Redesigning aortic endograft: enabling in-situ personalized aneurysm healingEPEIUS aims to revolutionize aortic aneurysm treatment by developing a bioengineered, 3D-printed, drug-loaded endograft for early personalized healing through innovative in-vitro models. | ERC Consolid... | € 1.991.225 | 2024 | Details |
Piezoceutical biomaterial scaffolds for immunomodulatory-based myocardial repairThe PiezoMac patch aims to regenerate cardiac muscle post-myocardial infarction using optimized piezoelectric stimulation and 3D-printed designs tailored to patient-specific heart anatomy. | ERC Consolid... | € 2.579.608 | 2024 | Details |
Pushing Boundaries in Pre-clinical Aortopathy ResearchThis project aims to unravel mechanisms of syndromic thoracic aortic aneurysm and develop effective therapies using patient-derived aorta-on-a-chip models for pre-clinical research. | ERC Starting... | € 1.494.848 | 2024 | Details |
Rejuvenation of the Intervertebral Disc Using Self-Healing Biomimetic Extracellular Matrix Biomaterial Tissue AdhesivesThis project aims to develop a self-healing biomimetic hydrogel for treating degenerated intervertebral discs, restoring tissue properties and improving patient outcomes in minimally invasive spine treatments. | ERC Proof of... | € 150.000 | 2024 | Details |
Ontwikkeling van een waterdichte, afsluitende patch ter voorkoming van hersenvocht lekkage na neurochirurgische operatiesPolyganics en Elana ontwikkelen een synthetische patch voor een waterdichte sluiting van de dura na neurochirurgie, om complicaties te verminderen en de patiëntkwaliteit te verbeteren. | Mkb-innovati... | € 200.000 | 2015 | Details |
Redesigning aortic endograft: enabling in-situ personalized aneurysm healing
EPEIUS aims to revolutionize aortic aneurysm treatment by developing a bioengineered, 3D-printed, drug-loaded endograft for early personalized healing through innovative in-vitro models.
Piezoceutical biomaterial scaffolds for immunomodulatory-based myocardial repair
The PiezoMac patch aims to regenerate cardiac muscle post-myocardial infarction using optimized piezoelectric stimulation and 3D-printed designs tailored to patient-specific heart anatomy.
Pushing Boundaries in Pre-clinical Aortopathy Research
This project aims to unravel mechanisms of syndromic thoracic aortic aneurysm and develop effective therapies using patient-derived aorta-on-a-chip models for pre-clinical research.
Rejuvenation of the Intervertebral Disc Using Self-Healing Biomimetic Extracellular Matrix Biomaterial Tissue Adhesives
This project aims to develop a self-healing biomimetic hydrogel for treating degenerated intervertebral discs, restoring tissue properties and improving patient outcomes in minimally invasive spine treatments.
Ontwikkeling van een waterdichte, afsluitende patch ter voorkoming van hersenvocht lekkage na neurochirurgische operaties
Polyganics en Elana ontwikkelen een synthetische patch voor een waterdichte sluiting van de dura na neurochirurgie, om complicaties te verminderen en de patiëntkwaliteit te verbeteren.