SubsidieMeestersTHE NEXT STENT GENERATION: A FIRST-IN-CLASS REGENERATIVE NANOFIBER STENT TO RECONSTRUCT ARTERIES FROM THE INSIDE OUT
STENTiT aims to revolutionize BTK-CLI treatment with a regenerative stent that promotes vascular restoration and reduces complications, seeking €2.5M in grants and €10M in equity for clinical studies.
Projectdetails
Introduction
Below-the-knee critical limb ischemia (BTK-CLI) is the severe blockage of the arteries in the limb, leading to reduced blood flow. This condition currently affects over 3.5 million people in the EU and US.
Current Treatment Challenges
The current standard of care for BTK-CLI is balloon angioplasty. Unfortunately, this treatment has failed to show strong clinical outcomes:
- Around 40% of patients suffer from procedural complications.
- 73% of cases develop restenosis within 3 months.
- 25% of patients end up requiring minor or major limb amputations.
Innovative Solution
STENTiT has developed a first-in-class stent with regenerative capacity, representing a paradigm shift for medical stents.
Features of the Regenerative Stent
- The Regenerative Stent is fully composed of nanofibers, allowing for unique vascular restoration.
- The stent gradually dissolves while new vascular tissue is being formed, fully rebuilding the artery to secure long-term patency.
Funding Request
STENTiT requests a €2.5 million grant and €10 million in equity to complete the clinical studies and prepare the Regenerative Stent for market launch.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.500.000 |
| Totale projectbegroting | € 4.901.667 |
Tijdlijn
| Startdatum | 1-9-2023 |
| Einddatum | 31-8-2025 |
| Subsidiejaar | 2023 |
Partners & Locaties
Projectpartners
- STENTIT B.V.penvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
"The NIMBLE System: A novel non-invasive and non-ionizing medical device for the continous monitoring of patients with implanted cardiovascular stents"""NIMBLE Diagnostics is developing a microwave-based device for non-invasive stent monitoring, aiming to shift from reactive to proactive care and improve patient outcomes. | EIC Accelerator | € 2.306.500 | 2024 | Details |
Clinical validation of the First Implantable Sensor System for Wireless detection of stent occlusion/ restenosisVesselSens is developing StentGuard, a smart device for early, non-invasive detection of restenosis in PAD patients to improve outcomes and reduce healthcare costs. | EIC Accelerator | € 2.500.000 | 2022 | Details |
Transformational crossing system to prevent amputation and treat complex chronic total occlusions in critical limb ischemiaVersono's CTO guidewire uses ultrasound to enable endovascular surgeons to effectively treat 90% of chronic total occlusions, aiming to restore blood flow and prevent limb amputation in CLTI patients. | EIC Accelerator | € 2.478.175 | 2023 | Details |
Next-generation heart bypass grafts to naturally restore cardiovascular function.Xeltis aims to clinically validate a restorative vascular graft (XABG) to treat coronary artery disease without vein harvesting, enhancing patient outcomes and reducing healthcare costs. | EIC Accelerator | € 2.481.701 | 2022 | Details |
Minimally invasive suturing for vascular bore closure and heart defect repairNovelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures. | EIC Accelerator | € 2.499.999 | 2024 | Details |
"The NIMBLE System: A novel non-invasive and non-ionizing medical device for the continous monitoring of patients with implanted cardiovascular stents"""
NIMBLE Diagnostics is developing a microwave-based device for non-invasive stent monitoring, aiming to shift from reactive to proactive care and improve patient outcomes.
Clinical validation of the First Implantable Sensor System for Wireless detection of stent occlusion/ restenosis
VesselSens is developing StentGuard, a smart device for early, non-invasive detection of restenosis in PAD patients to improve outcomes and reduce healthcare costs.
Transformational crossing system to prevent amputation and treat complex chronic total occlusions in critical limb ischemia
Versono's CTO guidewire uses ultrasound to enable endovascular surgeons to effectively treat 90% of chronic total occlusions, aiming to restore blood flow and prevent limb amputation in CLTI patients.
Next-generation heart bypass grafts to naturally restore cardiovascular function.
Xeltis aims to clinically validate a restorative vascular graft (XABG) to treat coronary artery disease without vein harvesting, enhancing patient outcomes and reducing healthcare costs.
Minimally invasive suturing for vascular bore closure and heart defect repair
Novelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
NanoStentDit project ontwikkelt een volledig opneembare stent voor de behandeling van kritische ischemie, ter vermindering van amputaties en zorgkosten. | Mkb-innovati... | € 350.000 | 2022 | Details |
Wireless Stent-like Soft Millirobots (STENTBOT) for Minimally Invasive Brain Vasculature Disease TreatmentsThe project aims to develop a wireless stent-shaped magnetic soft millirobot for minimally invasive treatment of brain vascular diseases, enabling safe access and repositioning for targeted drug delivery. | ERC Proof of... | € 150.000 | 2022 | Details |
Polymer-based Stealth Coating of Hemocompatible and Absorbable StentsThe StealthStent project aims to create a resorbable stent for pediatric congenital heart disease, reducing foreign body reactions and improving treatment outcomes for children and adults. | EIC Transition | € 2.495.679 | 2025 | Details |
Stent delivery deviceVenous Stent B.V. ontwikkelt een innovatief delivery device voor nauwkeurige plaatsing van de revolutionaire WStent. | Mkb-innovati... | € 20.000 | 2022 | Details |
Regenerative Stenting for Osteoporotic Vertebral Fracture RepairRESTORE aims to revolutionize osteoporotic vertebral fracture treatment by using 3D-printed biodegradable stents and thermoresponsive hydrogels for personalized bone regeneration and repair. | ERC Consolid... | € 2.039.473 | 2024 | Details |
NanoStent
Dit project ontwikkelt een volledig opneembare stent voor de behandeling van kritische ischemie, ter vermindering van amputaties en zorgkosten.
Wireless Stent-like Soft Millirobots (STENTBOT) for Minimally Invasive Brain Vasculature Disease Treatments
The project aims to develop a wireless stent-shaped magnetic soft millirobot for minimally invasive treatment of brain vascular diseases, enabling safe access and repositioning for targeted drug delivery.
Polymer-based Stealth Coating of Hemocompatible and Absorbable Stents
The StealthStent project aims to create a resorbable stent for pediatric congenital heart disease, reducing foreign body reactions and improving treatment outcomes for children and adults.
Stent delivery device
Venous Stent B.V. ontwikkelt een innovatief delivery device voor nauwkeurige plaatsing van de revolutionaire WStent.
Regenerative Stenting for Osteoporotic Vertebral Fracture Repair
RESTORE aims to revolutionize osteoporotic vertebral fracture treatment by using 3D-printed biodegradable stents and thermoresponsive hydrogels for personalized bone regeneration and repair.