SubsidieMeestersWorld's first device-based treatment for small abdominal aortic aneurysms based on revolutionary new treatment paradigm
The Angiolutions device is a minimally-invasive implant that stabilizes small abdominal aortic aneurysms by increasing aortic stiffness, preventing life-threatening progression.
Projectdetails
Introduction
The Angiolutions device is a first-of-its-kind device stopping the life-threatening progression of small abdominal aortic aneurysm (AAA) – a pathological dilation of the aorta.
Innovation
Angiolutions’ award-winning & patent-protected solution leverages a fundamentally new understanding of AAA growth discovered by the founders at Stanford University. They showed that stiffness gradients between the compliant (healthy) aorta and the adjacent stiff (diseased) aneurysm serve as a motor for AAA growth.
Development
Based on this principle and together with key physicians, we developed a minimally-invasive, non-active aortic implant (class III).
- The nitinol-based device is positioned adjacent to the aneurysm sack via simple, catheter-based implantation.
- It is specifically designed to focally increase aortic stiffness in the compliant AAA neck region.
- This design reduces stiffness gradients towards the stiff AAA sack that drive aneurysm growth.
Conclusion
Hereby, we achieve a fast, low-risk, size-stabilizing treatment of small AAA.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.499.999 |
| Totale projectbegroting | € 3.999.673 |
Tijdlijn
| Startdatum | 1-1-2024 |
| Einddatum | 31-12-2025 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- ANGIOLUTIONS GMBHpenvoerder
Land(en)
Geen landeninformatie beschikbaar
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
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Revolutionary vascular repair patch to treat aortic dissectionsAortyx's biomimetic bioresorbable adhesive patch aims to treat aortic dissections via endovascular deployment, enhancing natural repair and reducing mortality compared to traditional stents. | EIC Accelerator | € 2.500.000 | 2022 | Details |
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A minimally invasive and durable endograft fastening solution for Abdominal Aortic Aneurysm (AAA)
Aortoseal is an innovative implant for endovascular aneurysm repair that combines the stability of open surgery with the safety of EVAR, aiming to improve patient outcomes and save healthcare costs.
Minimally invasive suturing for vascular bore closure and heart defect repair
Novelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures.
Revolutionary vascular repair patch to treat aortic dissections
Aortyx's biomimetic bioresorbable adhesive patch aims to treat aortic dissections via endovascular deployment, enhancing natural repair and reducing mortality compared to traditional stents.
"The NIMBLE System: A novel non-invasive and non-ionizing medical device for the continous monitoring of patients with implanted cardiovascular stents"""
NIMBLE Diagnostics is developing a microwave-based device for non-invasive stent monitoring, aiming to shift from reactive to proactive care and improve patient outcomes.
Bypassing open heart surgery with Excimer Laser Assisted Non Occlusive Anastomosis (ELANA®)
AMT Medical aims to revolutionize coronary artery disease treatment by developing a minimally invasive, cost-effective CABG surgery using innovative ELANA technology, seeking $7.5M for clinical validation and market entry.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Pushing Boundaries in Pre-clinical Aortopathy ResearchThis project aims to unravel mechanisms of syndromic thoracic aortic aneurysm and develop effective therapies using patient-derived aorta-on-a-chip models for pre-clinical research. | ERC Starting... | € 1.494.848 | 2024 | Details |
Redesigning aortic endograft: enabling in-situ personalized aneurysm healingEPEIUS aims to revolutionize aortic aneurysm treatment by developing a bioengineered, 3D-printed, drug-loaded endograft for early personalized healing through innovative in-vitro models. | ERC Consolid... | € 1.991.225 | 2024 | Details |
Prognostic assessment of valvular aortic disease treatment coupling Immunological and biomechanical profilesProtego aims to develop a predictive methodology combining immunological and biomechanical profiles to optimize treatment timing and outcomes for patients with aortic valve diseases, reducing complications. | ERC Starting... | € 1.498.295 | 2024 | Details |
Fluid-Structure Interaction and Machine Leaning for Controlling Unruptured Intracranial AneurysmsThis project aims to enhance intracranial aneurysm treatment by developing predictive models and novel stent designs using advanced computational methods and deep reinforcement learning. | ERC Consolid... | € 1.891.333 | 2023 | Details |
MicroHeartHet project ontwikkelt een gestandaardiseerd productieproces voor de ELANA Heart Bypass, een minimaal-invasieve behandeling voor coronaire hartziekten, ter verbetering van patiëntenzorg en commercialisatie. | Mkb-innovati... | € 155.525 | 2018 | Details |
Pushing Boundaries in Pre-clinical Aortopathy Research
This project aims to unravel mechanisms of syndromic thoracic aortic aneurysm and develop effective therapies using patient-derived aorta-on-a-chip models for pre-clinical research.
Redesigning aortic endograft: enabling in-situ personalized aneurysm healing
EPEIUS aims to revolutionize aortic aneurysm treatment by developing a bioengineered, 3D-printed, drug-loaded endograft for early personalized healing through innovative in-vitro models.
Prognostic assessment of valvular aortic disease treatment coupling Immunological and biomechanical profiles
Protego aims to develop a predictive methodology combining immunological and biomechanical profiles to optimize treatment timing and outcomes for patients with aortic valve diseases, reducing complications.
Fluid-Structure Interaction and Machine Leaning for Controlling Unruptured Intracranial Aneurysms
This project aims to enhance intracranial aneurysm treatment by developing predictive models and novel stent designs using advanced computational methods and deep reinforcement learning.
MicroHeart
Het project ontwikkelt een gestandaardiseerd productieproces voor de ELANA Heart Bypass, een minimaal-invasieve behandeling voor coronaire hartziekten, ter verbetering van patiëntenzorg en commercialisatie.