SubsidieMeesters"The NIMBLE System: A novel non-invasive and non-ionizing medical device for the continous monitoring of patients with implanted cardiovascular stents"""
NIMBLE Diagnostics is developing a microwave-based device for non-invasive stent monitoring, aiming to shift from reactive to proactive care and improve patient outcomes.
Projectdetails
Introduction
At NIMBLE Diagnostics, we are developing a first-in-class microwave-based medical device for the non-invasive and non-ionizing monitoring of patients with implanted stents.
Background
Stents are one of the most implanted devices worldwide and are used to re-open blocked arteries and restore the correct flow of blood or other fluids. They are especially useful to prevent heart attacks or to treat their lasting symptoms. However, after implantation, stents become blocked or damaged in 30% of cases. Symptoms only appear after a stent is already 90% dysfunctional, which increases the incidence of serious complications, including strokes, heart attacks, or sudden death.
Current Diagnosis Methods
Diagnosis of malfunctioning stents is still symptom-driven and is based on an invasive procedure called catheter angiography. This procedure involves:
- Anesthesia
- X-ray exposure
- 24-hour hospitalization recovery
This complex, costly, and invasive procedure is not appropriate for ongoing monitoring, which is why the standard of care only reacts when patients already have potentially life-threatening symptoms.
NIMBLE System
The NIMBLE System can read the electromagnetic signature of any stent non-invasively in less than 5 seconds. It can be used to provide information on stent status and malfunction during regular clinical visits. Thus, NIMBLE enables early treatments to prevent negative outcomes and personalization of therapy, shifting from reactive to proactive care.
Current Status
Our technology is currently at TRL5/6, with an MVP that has shown excellent results in pre-clinical validations. We have also started the first-in-human testing in a pilot study of 30 patients that will finish in early 2024.
Future Plans
The EIC Accelerator program will allow us to bridge the biggest risk of our project by performing the regulatory clinical trial to obtain the CE mark. Additionally, it will support us in creating and accessing a multi-billion blue ocean market opportunity. This will allow us to establish NIMBLE as a European leader in the future of implant diagnostics and aid millions of patients worldwide.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.306.500 |
| Totale projectbegroting | € 3.295.000 |
Tijdlijn
| Startdatum | 1-2-2024 |
| Einddatum | 31-1-2026 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- NIMBLE DIAGNOSTICS SLpenvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Clinical validation of the First Implantable Sensor System for Wireless detection of stent occlusion/ restenosisVesselSens is developing StentGuard, a smart device for early, non-invasive detection of restenosis in PAD patients to improve outcomes and reduce healthcare costs. | EIC Accelerator | € 2.500.000 | 2022 | Details |
An AI powered turn-key solution for MRI based interventional cardiologyNano4Imaging aims to deliver TRACKR, a B2B platform enhancing MRI-guided interventional radiology with nano-coatings and real-time tracking software for commercial device makers. | EIC Accelerator | € 2.482.709 | 2023 | Details |
Paradigm shift in stroke: accurate diagnosis and evaluation of all treatment options in any hospital, at any timeMethinks aims to transform stroke diagnosis by enabling all hospitals to evaluate treatment options using standard imaging, reducing time-to-treatment and improving patient outcomes globally. | EIC Accelerator | € 2.495.415 | 2023 | Details |
Minimally invasive suturing for vascular bore closure and heart defect repairNovelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures. | EIC Accelerator | € 2.499.999 | 2024 | Details |
THE NEXT STENT GENERATION: A FIRST-IN-CLASS REGENERATIVE NANOFIBER STENT TO RECONSTRUCT ARTERIES FROM THE INSIDE OUTSTENTiT aims to revolutionize BTK-CLI treatment with a regenerative stent that promotes vascular restoration and reduces complications, seeking €2.5M in grants and €10M in equity for clinical studies. | EIC Accelerator | € 2.500.000 | 2023 | Details |
Clinical validation of the First Implantable Sensor System for Wireless detection of stent occlusion/ restenosis
VesselSens is developing StentGuard, a smart device for early, non-invasive detection of restenosis in PAD patients to improve outcomes and reduce healthcare costs.
An AI powered turn-key solution for MRI based interventional cardiology
Nano4Imaging aims to deliver TRACKR, a B2B platform enhancing MRI-guided interventional radiology with nano-coatings and real-time tracking software for commercial device makers.
Paradigm shift in stroke: accurate diagnosis and evaluation of all treatment options in any hospital, at any time
Methinks aims to transform stroke diagnosis by enabling all hospitals to evaluate treatment options using standard imaging, reducing time-to-treatment and improving patient outcomes globally.
Minimally invasive suturing for vascular bore closure and heart defect repair
Novelrad's NVCD closure device aims to minimize complications in large-bore vascular closures during cardiac surgeries through innovative micro-suturing technology, facilitating safer and faster procedures.
THE NEXT STENT GENERATION: A FIRST-IN-CLASS REGENERATIVE NANOFIBER STENT TO RECONSTRUCT ARTERIES FROM THE INSIDE OUT
STENTiT aims to revolutionize BTK-CLI treatment with a regenerative stent that promotes vascular restoration and reduces complications, seeking €2.5M in grants and €10M in equity for clinical studies.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
NanoStentDit project ontwikkelt een volledig opneembare stent voor de behandeling van kritische ischemie, ter vermindering van amputaties en zorgkosten. | Mkb-innovati... | € 350.000 | 2022 | Details |
Novel microsensing platform for remote patient monitoringThe FORESEE project aims to advance implantable microstimulators for remote monitoring of chronic heart failure, enhancing patient care and market access for 10.5 million potential users. | EIC Transition | € 2.499.051 | 2023 | Details |
In-vessel implantable smart sensing device for personalised medicineThe IV-Lab project develops a miniaturized implantable sensor for continuous health monitoring in cardiovascular patients, enabling personalized medical interventions and reducing hospitalizations. | EIC Pathfinder | € 4.158.610 | 2023 | Details |
A Novel Handheld Ultrasound Medical Imaging Probe: Prototyping, Initial Validation and Business DevelopmentThe LucidWave Project aims to develop a low-cost, advanced handheld ultrasound probe for improved bedside diagnostics, enhancing medical decision-making and reducing misdiagnosis. | EIC Transition | € 2.427.025 | 2022 | Details |
Speckle Technology and Digital Biomarkers of Microvascular Function for Monitoring Cardiovascular DiseasesThe project aims to develop innovative monitoring instruments for early detection of cardiovascular diseases, integrating advanced technologies to reduce healthcare burdens and costs in the EU. | EIC Pathfinder | € 3.979.006 | 2023 | Details |
NanoStent
Dit project ontwikkelt een volledig opneembare stent voor de behandeling van kritische ischemie, ter vermindering van amputaties en zorgkosten.
Novel microsensing platform for remote patient monitoring
The FORESEE project aims to advance implantable microstimulators for remote monitoring of chronic heart failure, enhancing patient care and market access for 10.5 million potential users.
In-vessel implantable smart sensing device for personalised medicine
The IV-Lab project develops a miniaturized implantable sensor for continuous health monitoring in cardiovascular patients, enabling personalized medical interventions and reducing hospitalizations.
A Novel Handheld Ultrasound Medical Imaging Probe: Prototyping, Initial Validation and Business Development
The LucidWave Project aims to develop a low-cost, advanced handheld ultrasound probe for improved bedside diagnostics, enhancing medical decision-making and reducing misdiagnosis.
Speckle Technology and Digital Biomarkers of Microvascular Function for Monitoring Cardiovascular Diseases
The project aims to develop innovative monitoring instruments for early detection of cardiovascular diseases, integrating advanced technologies to reduce healthcare burdens and costs in the EU.