Neuromorphic Flexible Electro/chemical Interface for in-Memory Bio-Sensing and Computing.

Develop a miniaturized, self-contained biosensing technology using neuromorphic devices for real-time monitoring and classification of neurodegenerative biomarkers in individualized healthcare.

Subsidie
€ 1.500.000
2025

Projectdetails

Introduction

Efficient assessment of multiple bio/chemical and electrophysiology biomarkers directly at the area of interest is an indisputable asset in individualized healthcare. However, current implantable systems and bioelectronic technologies still face limitations in ultra-sensitive bio-sensing. They address the electrical and chemical aspects fragmentally and depend on complex setups and computationally heavy off-line processing.

Limitations of Current Technologies

Conventional von Neumann architectures face limitations in efficiently handling the increasing sensor output data. This can be mainly attributed to the physical separation between sensing, memory, and computing units.

Objective

The overall objective is to conceptualize a first-of-its-kind, miniaturized, and self-contained biosensing technology. This technology will employ neuromorphic devices functioning as on-node sensors and processors (in-memory (bio)sensing and computing) in soft, flexible, and bio-compatible materials and format.

Demonstration

I will demonstrate this technology by showcasing, in an in vivo animal model, a proof-of-concept implantable bio-interface. This interface will intelligently interrogate and classify neurodegenerative disease-related bio/chemical and electrical biomarkers. It will be coupled with active elements enabling precise adjustment of stimulation control parameters based on analog inputs.

Potential Impact

This technology holds great potential to advance our understanding and treatments of pathologies through multiplex electrical and chemical monitoring. It aims to reduce the demands for power-intensive analog-to-digital conversion and computational processing. Furthermore, it paves the way for tailored interventions, laying the foundation for next-generation biomedical modulation systems.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 1.500.000
Totale projectbegroting€ 1.500.000

Tijdlijn

Startdatum1-1-2025
Einddatum31-12-2029
Subsidiejaar2025

Partners & Locaties

Projectpartners

  • UNIVERSITEIT GENTpenvoerder
  • UNIVERSITA DEGLI STUDI DI PADOVA

Land(en)

BelgiumItaly

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