Regenerative Engineering of Living Autologous Interfaces
RELAI aims to develop innovative bioelectronic technologies for neural interfacing to enhance information transduction and treat chronic conditions through advanced biohybrid interfaces.
Projectdetails
Introduction
RELAI will design and exploit a toolbox of innovative bioelectronic technologies and surgical constructs that will enable new possibilities in neural interfacing and revolutionise the way we transduce information to and from the human body.
Bioelectronics Overview
This new class of living bioelectronics will leverage bespoke electrode arrays and electrical stimulation paradigms to guide neural regeneration within autologous surgical constructs in vivo.
Hypothesis
The reinnervated constructs are hypothesised to form living high-resolution interfaces that will enable precise modulation of somatic and autonomic functions via injured and intact nerves.
Applications
This innovative class of biohybrid interfaces will enable a broad array of applications, including:
- Treatment of chronic conditions (such as diabetes)
- Enhanced operation of advanced neuroprostheses
- Realisation of supraphysiological sensing
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 150.000 |
Totale projectbegroting | € 150.000 |
Tijdlijn
Startdatum | 1-1-2025 |
Einddatum | 30-6-2026 |
Subsidiejaar | 2025 |
Partners & Locaties
Projectpartners
- IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINEpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
Project | Regeling | Bedrag | Jaar | Actie |
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MANUNKIND: Determinants and Dynamics of Collaborative ExploitationThis project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery. | ERC STG | € 1.497.749 | 2022 | Details |
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressureThe UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance. | ERC STG | € 1.498.280 | 2022 | Details |
Uncovering the mechanisms of action of an antiviral bacteriumThis project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function. | ERC STG | € 1.500.000 | 2023 | Details |
The Ethics of Loneliness and SociabilityThis project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field. | ERC STG | € 1.025.860 | 2023 | Details |
MANUNKIND: Determinants and Dynamics of Collaborative Exploitation
This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressure
The UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance.
Uncovering the mechanisms of action of an antiviral bacterium
This project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function.
The Ethics of Loneliness and Sociability
This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
Vergelijkbare projecten uit andere regelingen
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BioFunctional IntraNeural ElectrodesBioFINE aims to develop advanced flexible intraneural multielectrode arrays for improved long-term integration with peripheral nerves, enhancing bionic limb communication and neurotechnology. | EIC Pathfinder | € 1.945.622 | 2023 | Details |
Biodegradable MEMS implants for nerve repairDevelop biodegradable MEMS implants for nerve repair using innovative mechanical stimulation strategies to enhance neural regeneration post-injury. | ERC STG | € 1.672.968 | 2023 | Details |
Neuromorphic Learning in Organic Adaptive Biohybrid SystemsThis project aims to develop a neuromorphic bioelectronic platform for adaptive control of soft robotic actuators using organic materials and local biosignal modulation. | ERC COG | € 1.996.143 | 2024 | Details |
Hydrogel Machines for Seamless Living System InterfacesGELECTRO aims to develop electrically conductive hydrogels for bioelectronic interfaces that mimic biological systems, enhancing tissue repair and organoid development through advanced sensing and actuation. | ERC COG | € 1.999.473 | 2024 | Details |
BioFunctional IntraNeural Electrodes
BioFINE aims to develop advanced flexible intraneural multielectrode arrays for improved long-term integration with peripheral nerves, enhancing bionic limb communication and neurotechnology.
Biodegradable MEMS implants for nerve repair
Develop biodegradable MEMS implants for nerve repair using innovative mechanical stimulation strategies to enhance neural regeneration post-injury.
Neuromorphic Learning in Organic Adaptive Biohybrid Systems
This project aims to develop a neuromorphic bioelectronic platform for adaptive control of soft robotic actuators using organic materials and local biosignal modulation.
Hydrogel Machines for Seamless Living System Interfaces
GELECTRO aims to develop electrically conductive hydrogels for bioelectronic interfaces that mimic biological systems, enhancing tissue repair and organoid development through advanced sensing and actuation.