SubsidieMeestersRegenerative Engineering of Living Autologous Interfaces
RELAI aims to develop innovative bioelectronic technologies for neural interfacing to enhance information transduction and treat chronic conditions through advanced biohybrid interfaces.
Projectdetails
Introduction
RELAI will design and exploit a toolbox of innovative bioelectronic technologies and surgical constructs that will enable new possibilities in neural interfacing and revolutionise the way we transduce information to and from the human body.
Technology Overview
This new class of living bioelectronics will leverage bespoke electrode arrays and electrical stimulation paradigms to guide neural regeneration within autologous surgical constructs in vivo.
Hypothesis
The reinnervated constructs are hypothesised to form living high-resolution interfaces that will enable precise modulation of somatic and autonomic functions via injured and intact nerves.
Applications
This innovative class of biohybrid interfaces will enable a broad array of applications, including:
- Treatment of chronic conditions (such as diabetes)
- Enhanced operation of advanced neuroprostheses
- Realisation of supraphysiological sensing
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-1-2025 |
| Einddatum | 30-6-2026 |
| Subsidiejaar | 2025 |
Partners & Locaties
Projectpartners
- IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINEpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
5D Electro-Mechanical Bio-Interface for Neuronal Tissue EngineeringDevelop a novel 3D biomaterial for leadless electrical and mechanical modulation to enhance brain research and neuroengineering applications. | ERC Starting... | € 1.750.000 | 2024 | Details |
Hydrogel Machines for Seamless Living System InterfacesGELECTRO aims to develop electrically conductive hydrogels for bioelectronic interfaces that mimic biological systems, enhancing tissue repair and organoid development through advanced sensing and actuation. | ERC Consolid... | € 1.999.473 | 2024 | Details |
Biodegradable MEMS implants for nerve repairDevelop biodegradable MEMS implants for nerve repair using innovative mechanical stimulation strategies to enhance neural regeneration post-injury. | ERC Starting... | € 1.672.968 | 2023 | Details |
Personalised Bioelectronics for Epithelial RepairProBER aims to develop personalized bioelectronic wound dressings using conformal DC electrodes to enhance healing speed and efficiency in chronic wounds, preparing for clinical studies. | ERC Proof of... | € 150.000 | 2023 | Details |
Neuromorphic Learning in Organic Adaptive Biohybrid SystemsThis project aims to develop a neuromorphic bioelectronic platform for adaptive control of soft robotic actuators using organic materials and local biosignal modulation. | ERC Consolid... | € 1.996.143 | 2024 | Details |
5D Electro-Mechanical Bio-Interface for Neuronal Tissue Engineering
Develop a novel 3D biomaterial for leadless electrical and mechanical modulation to enhance brain research and neuroengineering applications.
Hydrogel Machines for Seamless Living System Interfaces
GELECTRO aims to develop electrically conductive hydrogels for bioelectronic interfaces that mimic biological systems, enhancing tissue repair and organoid development through advanced sensing and actuation.
Biodegradable MEMS implants for nerve repair
Develop biodegradable MEMS implants for nerve repair using innovative mechanical stimulation strategies to enhance neural regeneration post-injury.
Personalised Bioelectronics for Epithelial Repair
ProBER aims to develop personalized bioelectronic wound dressings using conformal DC electrodes to enhance healing speed and efficiency in chronic wounds, preparing for clinical studies.
Neuromorphic Learning in Organic Adaptive Biohybrid Systems
This project aims to develop a neuromorphic bioelectronic platform for adaptive control of soft robotic actuators using organic materials and local biosignal modulation.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
BioFunctional IntraNeural ElectrodesBioFINE aims to develop advanced flexible intraneural multielectrode arrays for improved long-term integration with peripheral nerves, enhancing bionic limb communication and neurotechnology. | EIC Pathfinder | € 1.945.622 | 2023 | Details |
IMPROVING THE EFFECTIVENESS AND SAFETY OF EPIGENETIC EDITING IN BRAIN REGENERATIONREGENERAR aims to develop a non-viral delivery system to reprogram glial cells into neurons for treating CNS injuries, focusing on safety, targeting, and stakeholder collaboration. | EIC Pathfinder | € 2.943.233 | 2024 | Details |
Piezo-driven theramesh: A revolutionary multifaceted actuator to repair the injured spinal cordPiezo4Spine aims to create a groundbreaking 3D bioprinted mesh therapy for spinal cord injury that enhances neural repair through targeted mechanotransduction and gene therapy. | EIC Pathfinder | € 3.537.120 | 2023 | Details |
Advanced Intelligent stimulation device: HAND movement restorationThe AI-HAND project aims to develop an advanced ASIC-based implanted device with self-adapting electrodes to restore hand movements in quadriplegic patients through innovative nerve stimulation techniques. | EIC Pathfinder | € 2.999.834 | 2023 | Details |
BRAIN-SPINE INTERFACES TO REVERSE UPPER- AND LOWER-LIMB PARALYSISDeveloping fully-implantable brain-spine interfaces to restore movement in individuals with chronic paralysis through advanced neurosensors and neurostimulation systems. | EIC Transition | € 2.490.802 | 2022 | Details |
BioFunctional IntraNeural Electrodes
BioFINE aims to develop advanced flexible intraneural multielectrode arrays for improved long-term integration with peripheral nerves, enhancing bionic limb communication and neurotechnology.
IMPROVING THE EFFECTIVENESS AND SAFETY OF EPIGENETIC EDITING IN BRAIN REGENERATION
REGENERAR aims to develop a non-viral delivery system to reprogram glial cells into neurons for treating CNS injuries, focusing on safety, targeting, and stakeholder collaboration.
Piezo-driven theramesh: A revolutionary multifaceted actuator to repair the injured spinal cord
Piezo4Spine aims to create a groundbreaking 3D bioprinted mesh therapy for spinal cord injury that enhances neural repair through targeted mechanotransduction and gene therapy.
Advanced Intelligent stimulation device: HAND movement restoration
The AI-HAND project aims to develop an advanced ASIC-based implanted device with self-adapting electrodes to restore hand movements in quadriplegic patients through innovative nerve stimulation techniques.
BRAIN-SPINE INTERFACES TO REVERSE UPPER- AND LOWER-LIMB PARALYSIS
Developing fully-implantable brain-spine interfaces to restore movement in individuals with chronic paralysis through advanced neurosensors and neurostimulation systems.