Next-gen fluorescence imaging for research and theranostics

Introduction

Fluorescence microscopy is a key technique in the life sciences, though the method struggles to deliver fast and sensitive imaging of multicellular systems. Such samples are now becoming commonplace not only in research but also in clinical use, including spatially-resolved 'omics' and theranostics based on patient material that allow the development of personalized treatments. However, their general uptake is limited by the absence of suitable instrumentation.

Project Overview

As part of our ERC-funded research, we have invented the TriScanner, a novel fluorescence microscope that offers transformative imaging performance, including:

• Much faster imaging
• Higher resolution
• Higher sensitivity

The TriScanner is also simple, robust, and affordable. It readily addresses an urgent need in current research and healthcare, and is well-positioned to scale out from research into 'workhorse' usage in industrial R&D and diagnostics.

Development Goals

We propose to develop this idea from a concept and lab prototype into a robust demonstrator that will be showcased on a variety of highly relevant applications. Our goals include:

1. Raising user awareness
2. Interacting with key leaders in academia
3. Collaborating with leading commercial partners

Market Exploration

This project will furthermore allow us to explore the business case and market potential, in view of developing and selecting the optimal valorization track.

Expected Impact

We expect to deliver societal impact by providing unprecedented new imaging capabilities in a fast-moving and highly influential research field.