Hyper-Realistic Models for Hands-On Surgical Training in Non-human Primate Biomedical Research

The PRISM project aims to develop a hyper-realistic model for ethical neurosurgical training in non-human primates, enhancing skills while promoting animal welfare and research quality.

Subsidie
€ 150.000
2024

Projectdetails

Introduction

The PRISM project addresses critical challenges in neurosurgical training involving non-human primates (NHPs) within the framework of the 3Rs (Replacement, Reduction, Refinement) endorsed by the EU. NHPs are indispensable models in biomedical research, particularly in neurosciences, due to their close phylogenetic relationship with humans.

Ethical Considerations

However, invasive procedures on NHPs, including cranial surgeries and targeted ablations, pose ethical dilemmas and require highly skilled personnel. This project introduces a groundbreaking solution by developing the first hyper-realistic model for hands-on surgical training in NHPs.

Collaboration and Objectives

Collaborating with UpSurgeOn, experts in 3D simulation for human neurosurgery, PRISM aims to create a safe and ethical training environment for young researchers working with NHPs. The project's objectives include:

  1. The design of a hyper-realistic NHP model
  2. The organization of pilot courses
  3. Devising strategies for commercialization

Expected Outcomes

PRISM promises enhanced visualization, tactile learning experiences, customizability, and ethical training, ultimately fostering career development, animal welfare, and research quality.

Conclusion

Successful implementation will set a new standard in NHP neurosurgical education with global potential.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 150.000
Totale projectbegroting€ 150.000

Tijdlijn

Startdatum1-8-2024
Einddatum31-1-2026
Subsidiejaar2024

Partners & Locaties

Projectpartners

  • TILBURG UNIVERSITY- UNIVERSITEIT VAN TILBURGpenvoerder
  • UPSURGEON SRL

Land(en)

NetherlandsItaly

Vergelijkbare projecten binnen European Research Council

ERC Proof of...

Against prostheses abandonment: immersive and low-cost platform for the rehabilitation of upper-limb amputees

BRAINmade aims to reduce upper-limb prosthesis abandonment by integrating EMG-controlled VR training to enhance motor skills and acceptance, transforming rehabilitation practices for amputees.

€ 150.000
ERC Starting...

Mechanics-augmented brain surgery

The MAGERY project seeks to enhance brain surgery by integrating mechanics-based simulations with VR/AR to minimize tissue damage and improve surgical outcomes.

€ 2.229.523
ERC Proof of...

Human skeletal muscle platform for disease modelling and high-throughput drug screening

Developing a high-throughput in vitro platform with biomimetic skeletal muscle analogues to model neuromuscular disorders for effective drug screening and therapy validation.

€ 150.000
ERC Synergy ...

A sonogenetic brain-machine interface for neurosciences and visual restoration

Developing a novel sonogenetic brain-machine interface for remote, precise control of neuronal networks in large primate brains to advance treatments for neurological disorders.

€ 7.817.939
ERC Consolid...

Towards Artificial Human Embryoid Models: Engineered and Synthetic Platforms for Ex Utero Mammalian Embryogenesis

Develop biotechnological platforms to culture mammalian embryos ex utero and create synthetic embryoids for advancing stem cell research and disease modeling.

€ 2.000.000

Vergelijkbare projecten uit andere regelingen

Mkb-innovati...

Onderzoek naar 3D geprinte fantomen voor trainingsdoeleinden en vergemakkelijken klinische validatie

Het project richt zich op het ontwikkelen van 3D geprinte flexibele en transparante structuren voor training en simulatie in cardiovasculaire chirurgie, met als doel efficiëntie en haptische feedback te verbeteren.

€ 20.000
EIC Pathfinder

Revolutionary high-resolution human 3D brain organoid platform integrating AI-based analytics

The 3D-BrAIn project aims to develop a personalized bio-digital twin of the human brain using advanced organoid cultures and machine learning to enhance precision medicine for CNS disorders.

€ 1.998.347
EIC Pathfinder

Transforming brain surgery by advancing functional-guided neuronavigational imaging

HyperProbe is an innovative all-optical imaging system using hyperspectral imaging and AI to enhance intraoperative neuronavigation and biomarker analysis during brain tumor surgeries.

€ 3.360.825
Mkb-innovati...

ADAM-X-Heart

Utrecht Preclinical en Medical-X ontwikkelen ADAM-X-Heart, een proefdiervrije simulator voor hartchirurgische training, om de kwaliteit, capaciteit en kosten van opleidingen te verbeteren.

€ 329.735
1.1 - Het ve...

High Fidelity Simulator

Het project ontwikkelt een highfidelity simulatieplatform voor de training van cardiovasculaire chirurgen met patiëntspecifieke organen.

€ 100.000