SubsidieMeestersDesigning green and energy-efficient anti-dewetting protocols for liquid chromatography
NODRY aims to create a simulation testbed to design HPLC protocols that mitigate dewetting in nanoporous materials, enabling environmentally friendly chromatography with pure water.
Projectdetails
Introduction
High Performance Liquid Chromatography (HPLC) is the leading separation technology in research and industry, which often relies on potentially hazardous and environmentally harmful organic solvents.
Environmental Considerations
Water is the ideal environmentally friendly mobile phase, which would open the way to green HPLC. However, its broad applicability is hindered by the phenomenon of dewetting of the stationary phase – the formation of bubbles in the hydrophobic nanoporous material – which makes it unavailable to the substances that need to be separated (“retention loss”).
Project Proposal
NODRY proposes to develop a unique, experimentally validated simulation testbed based on the PI expertise in theory and simulation of dewetting of nanopores acquired in ERC-StG HyGate.
Objectives
These simulation tools will be deployed to:
- Rationally design HPLC protocols capable of eliminating or alleviating the problem of dewetting in most HPLC columns operating with pure water as the solvent.
- Open the way to a green and energy-efficient chromatography.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-5-2022 |
| Einddatum | 31-10-2023 |
| Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZApenvoerder
- CENTRO DE INVESTIGACION COOPERATIVA DE ENERGIAS ALTERNATIVAS FUNDACION, CIC ENERGIGUNE FUNDAZIOA
Land(en)
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