SubsidieMeestersCommercial feasibility of a cell-free reactor setup for optimisation of complex enzymatic pathways
This project aims to commercialize a continuous stirred tank reactor for optimizing complex enzymatic pathways, enhancing production efficiency and establishing a viable commercialization strategy.
Projectdetails
Introduction
This project will explore the commercial feasibility of the first continuous stirred tank reactor solution for the synthetic replication and optimisation of complex enzymatic pathways.
Technology Overview
Our technology provides an urgently needed alternative for bioengineered organisms.
Challenges Addressed
Where normally raw materials of varying quality, competition between intermediates, toxicity, complex networks of feedback loops, and other poorly understood factors limit production rates, our approach can be used to converge effectively to optimised biochemistry.
Project Objectives
As part of the project, we will:
- Establish two industrially relevant pathways.
- Advance the software solution of our platform.
- Develop a commercialisation strategy.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-7-2022 |
| Einddatum | 31-12-2023 |
| Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- STICHTING RADBOUD UNIVERSITEITpenvoerder
Land(en)
Geen landeninformatie beschikbaar
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Continuous Enzyme Evolution – solving bottlenecks in enzyme engineering to design next-generation biocatalystsThe ContiZymes project aims to develop a scalable continuous evolution platform for rapidly engineering valuable biocatalysts, enhancing enzyme efficiency and mapping their functional properties. | ERC Consolid... | € 1.999.991 | 2024 | Details |
Development of rationally designed enzyme kitsKITZYME aims to create patentable enzyme kits for stereoselective carbon-carbon bond formation using advanced computational methods to enhance catalytic efficiency sustainably and cost-effectively. | ERC Proof of... | € 150.000 | 2024 | Details |
Systematic analyses and rational engineering of fast CO2 fixation pathways in living cellsFASTFIX aims to develop a novel method for quantifying enzyme kinetics in living E. coli to identify and engineer efficient synthetic CO2 fixation pathways, enhancing biotechnological production and CO2 mitigation. | ERC Starting... | € 1.499.980 | 2025 | Details |
Decellularised Extracellular Carpets for the Innovative Production of Human Engineered ReplicatesThis project aims to accelerate the development of cell-derived products using macromolecular crowding, enhancing European biotech competitiveness and creating new jobs and markets. | ERC Proof of... | € 150.000 | 2024 | Details |
Translating a new metabolic engineering strategy to industrial biotech applicationsThe TRANSMETECH project aims to translate the StrainBooster metabolic engineering strategy into industrial applications, enhancing bioprocess efficiency for sustainable chemical production. | ERC Proof of... | € 150.000 | 2023 | Details |
Continuous Enzyme Evolution – solving bottlenecks in enzyme engineering to design next-generation biocatalysts
The ContiZymes project aims to develop a scalable continuous evolution platform for rapidly engineering valuable biocatalysts, enhancing enzyme efficiency and mapping their functional properties.
Development of rationally designed enzyme kits
KITZYME aims to create patentable enzyme kits for stereoselective carbon-carbon bond formation using advanced computational methods to enhance catalytic efficiency sustainably and cost-effectively.
Systematic analyses and rational engineering of fast CO2 fixation pathways in living cells
FASTFIX aims to develop a novel method for quantifying enzyme kinetics in living E. coli to identify and engineer efficient synthetic CO2 fixation pathways, enhancing biotechnological production and CO2 mitigation.
Decellularised Extracellular Carpets for the Innovative Production of Human Engineered Replicates
This project aims to accelerate the development of cell-derived products using macromolecular crowding, enhancing European biotech competitiveness and creating new jobs and markets.
Translating a new metabolic engineering strategy to industrial biotech applications
The TRANSMETECH project aims to translate the StrainBooster metabolic engineering strategy into industrial applications, enhancing bioprocess efficiency for sustainable chemical production.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Haalbaarheidsonderzoek axiaal-radiaal reactor.Het project onderzoekt de haalbaarheid van een innovatieve, efficiënte en kleinere reactor voor de omzetting van CO2 en waterstof naar biobrandstoffen, met als doel kosten te verlagen en emissies te reduceren. | Mkb-innovati... | € 20.000 | 2021 | Details |
Automated online monitoring & control to improve processes and decision making in cell and gene therapy manufacturingThe project aims to develop an automated, self-contained bioreactor with continuous monitoring of critical process parameters to enhance scalability and quality in cell and gene therapy manufacturing. | EIC Pathfinder | € 3.617.783 | 2022 | Details |
TUNGSTEN BIOCATALYSIS – HEAVY METAL ENZYMES FOR SUSTAINABLE INDUSTRIAL BIOCATALYSISThis project aims to develop a new W-cofactor biosynthesis pathway in E. coli to produce tungsten-containing enzymes for sustainable chemical processes, enabling efficient CO2 reduction and cosmetic ingredient production. | EIC Pathfinder | € 2.430.574 | 2024 | Details |
Haalbaarheid van een innovatieve enzymsensor voor de voedingsindustrieHet project onderzoekt de haalbaarheid van goedkope biosensoren voor vroege detectie van contaminanten in de landbouw-, water- en voedselketen, met als doel voedselveiligheid en kwaliteit te verbeteren. | Mkb-innovati... | € 20.000 | 2023 | Details |
Biosensor Activated Biomanufacturing Scale-upEnduro aims to revolutionize microbial biomanufacturing with its synthetic biology plugin, Enduro Sense, to enable scalable processes and attract investment for commercial deployment. | EIC Accelerator | € 1.815.295 | 2023 | Details |
Haalbaarheidsonderzoek axiaal-radiaal reactor.
Het project onderzoekt de haalbaarheid van een innovatieve, efficiënte en kleinere reactor voor de omzetting van CO2 en waterstof naar biobrandstoffen, met als doel kosten te verlagen en emissies te reduceren.
Automated online monitoring & control to improve processes and decision making in cell and gene therapy manufacturing
The project aims to develop an automated, self-contained bioreactor with continuous monitoring of critical process parameters to enhance scalability and quality in cell and gene therapy manufacturing.
TUNGSTEN BIOCATALYSIS – HEAVY METAL ENZYMES FOR SUSTAINABLE INDUSTRIAL BIOCATALYSIS
This project aims to develop a new W-cofactor biosynthesis pathway in E. coli to produce tungsten-containing enzymes for sustainable chemical processes, enabling efficient CO2 reduction and cosmetic ingredient production.
Haalbaarheid van een innovatieve enzymsensor voor de voedingsindustrie
Het project onderzoekt de haalbaarheid van goedkope biosensoren voor vroege detectie van contaminanten in de landbouw-, water- en voedselketen, met als doel voedselveiligheid en kwaliteit te verbeteren.
Biosensor Activated Biomanufacturing Scale-up
Enduro aims to revolutionize microbial biomanufacturing with its synthetic biology plugin, Enduro Sense, to enable scalable processes and attract investment for commercial deployment.