NEW TECHNOLOGY FOR 1 MICRON RESOLUTION BIOMEDICAL IMAGING

The 1MICRON project aims to revolutionize cancer detection by developing high-resolution, integrated x-ray sensors for immediate surgical feedback, potentially saving over 100,000 treatments annually in Europe.

Subsidie
€ 2.999.999
2025

Projectdetails

Introduction

The 1MICRON project can bridge the gap in image quality between today’s digital x-ray detectors and histopathology. We will integrate CMOS electronics circuits directly into the sensor, employing an edge-on "deep silicon" geometry for monolithic sensors that ensure high efficiency.

Breakthrough in Imaging

This breakthrough promises a remarkable order of magnitude improvement in spatial resolution, all the way down to 1 micron. Such a high-resolution sensor will make phase contrast imaging much more practical and efficient, and as a secondary effect, this will dramatically increase the contrast in the images.

Impact on Pathology Analysis

Today’s pathology analysis takes weeks, and when cancer cells are found at the margin or in sentinel nodes, the patient is called back for corrective surgery, delaying treatment and decreasing survival chances. The 1MICRON imaging technology can be used directly in the operating room, providing a digitized 3D volume for immediate feedback on cancer margin.

Benefits to Healthcare

The new method can save over 100,000 surgical treatments per year only in Europe, saving the corresponding cost for the healthcare system. The technology could also be implemented in new markets such as developing countries, where today pathology laboratories are not accessible.

Secondary Objectives

A secondary objective is to provide a proof-of-principle for a new sensor for next-generation CT, coping with high x-ray flux and having low enough power consumption for future implementation in a clinical modality. The high resolution can provide a “3D virtual biopsy” as an alternative to today’s invasive needle biopsies.

Team Expertise

Our team includes leading European experts in medical imaging, phase-contrast imaging, monolithic sensor design, pathology, radiology, surgery, and industry, positioning us uniquely to undertake this ambitious project.

Conclusion

Our success can trigger a paradigm shift in both pathology and clinical x-ray imaging, corresponding to the most significant advancement in decades.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 2.999.999
Totale projectbegroting€ 2.999.999

Tijdlijn

Startdatum1-3-2025
Einddatum28-2-2029
Subsidiejaar2025

Partners & Locaties

Projectpartners

  • KUNGLIGA TEKNISKA HOEGSKOLANpenvoerder
  • KAROLINSKA INSTITUTET
  • TECHNISCHE UNIVERSITAET MUENCHEN
  • UNIVERSITA DEGLI STUDI DI TRENTO
  • ISTITUTO NAZIONALE DI FISICA NUCLEARE
  • PRISMATIC SENSORS AB

Land(en)

SwedenGermanyItaly

Vergelijkbare projecten binnen EIC Pathfinder

EIC Pathfinder

"Creation of innovative ""humidity to electricity"" renewable energy conversion technology towards sustainable energy challenge"

The CATCHER project aims to develop scalable technology for converting atmospheric humidity into renewable electricity, enhancing EU leadership in clean energy innovation.

€ 2.996.550
EIC Pathfinder

Quantitative Ultrasound Stochastic Tomography - Revolutionizing breast cancer diagnosis and screening with supercomputing-based radiation-free imaging.

The project aims to revolutionize breast cancer imaging by developing adjoint-based algorithms for uncertainty quantification, enhancing diagnostic confidence through high-resolution, radiation-free images.

€ 2.744.300
EIC Pathfinder

Dynamic Spatio-Temporal Modulation of Light by Phononic Architectures

Dynamo aims to revolutionize imaging technologies by enabling simultaneous light modulation at GHz rates, enhancing processing speed and positioning Europe as a leader in optical advancements.

€ 2.552.277
EIC Pathfinder

Emerging technologies for crystal-based gamma-ray light sources

TECHNO-CLS aims to develop novel gamma-ray light sources using oriented crystals and high-energy particle beams, enhancing applications in various scientific fields through innovative technology.

€ 2.643.187

Vergelijkbare projecten uit andere regelingen

ERC COG

Advanced X-ray Energy-sensitive Microscopy for Virtual Histology

This project aims to develop a prototype phase-contrast micro-CT scanner for non-invasive 3D histology to enhance volumetric analysis of tissue samples, particularly lung lesions.

€ 2.000.000
ERC ADG

In vivo Immunofluorescence-Optical Coherence Tomography

Develop a high-resolution endoscopic imaging system combining Optical Coherence Tomography and fluorescent antibodies for improved diagnosis and treatment of esophageal cancer and lung disease.

€ 2.500.000
ERC ADG

3D silicon detector for imaging of diagnostic and therapeutic nuclear medicine radiotracers with outstanding efficiency and high spatial resolution.

This project aims to develop a novel molecular imaging instrument using advanced silicon sensors to enhance efficiency and resolution, potentially revolutionizing medical imaging and related research fields.

€ 3.351.875
ERC POC

MUlti-spectral Scattering matrix for Enhanced skin imaging

The ERC REMINISCENCE project developed the DeepInsight microscope, enabling advanced non-invasive 3D imaging for early melanoma detection and skin disease analysis, with plans for commercialization.

€ 150.000