SubsidieMeestersBreakthrough Brain Stimulation Device for Epilepsy
EASEE is a minimally invasive device for focal cortical stimulation in epilepsy, using a unique quadrupolar electrode system for tailored high-frequency and DC-like stimulation to prevent seizures.
Projectdetails
Introduction
EASEE stands for epicranial application of stimulation electrodes in epilepsy. It is the first minimally invasive device for focal cortical stimulation.
Device Design
Based on the Laplace electrode (central electrode surrounded by a ring electrode), EASEE features 4 distinct electrodes replacing the outer ring. These electrodes are connected to 4 independent current sources to account for impedance and anatomical variances in the human skull.
Electric Field Characteristics
Still, the characteristic quadrupolar local electric field with high penetration depth is maintained.
Stimulation Pattern
The stimulation pattern is one of a kind. EASEE is equipped for:
- High frequency stimulation
- DC-like stimulation
- Low-frequency stimulation
Depending on the condition to be treated, the stimulation is tailored accordingly.
Application in Epilepsy
In epilepsy, intermittent high-frequency stimulation bursts throughout the day are combined with a 20-minute DC-like stimulation session. The first is meant to terminate upcoming seizures, while the second aims to initiate neuromodulatory processes to down-regulate the overexcitability of the epileptic brain area.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.495.836 |
| Totale projectbegroting | € 3.565.480 |
Tijdlijn
| Startdatum | 1-3-2023 |
| Einddatum | 28-2-2025 |
| Subsidiejaar | 2023 |
Partners & Locaties
Projectpartners
- PRECISIS GMBHpenvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
“EEG-based DIagnosis Support solutiON” (EDISON) to help close the epilepsy diagnosis gap in Low- and Middle-Income Countries (LMICs) by combining low CAPEX and AI-guided capture with telemedicineBrainCapture is developing an affordable EEG-based diagnosis service for epilepsy in LMICs, utilizing mobile technology and AI for remote analysis by neurologists to improve access to care. | EIC Accelerator | € 2.078.428 | 2022 | Details |
Brain Interchange ONE SR—the implantable neuromodulation technology for stroke rehabilitationCorTec aims to develop innovative implantable technology for stroke rehabilitation, enabling new therapies and devices while targeting market approval and $250M in sales by 2030. | EIC Accelerator | € 2.500.000 | 2022 | Details |
NAO.VNS: A New Personalized Neural Stimulation Therapy For Drug-resistant EpilepsyNAO.VNS is an innovative implantable vagus nerve stimulator using optical fibers to enhance treatment for drug-resistant epilepsy, enabling personalized therapy and remote monitoring, with market approval expected by 2028. | EIC Accelerator | € 2.499.000 | 2023 | Details |
“EEG-based DIagnosis Support solutiON” (EDISON) to help close the epilepsy diagnosis gap in Low- and Middle-Income Countries (LMICs) by combining low CAPEX and AI-guided capture with telemedicine
BrainCapture is developing an affordable EEG-based diagnosis service for epilepsy in LMICs, utilizing mobile technology and AI for remote analysis by neurologists to improve access to care.
Brain Interchange ONE SR—the implantable neuromodulation technology for stroke rehabilitation
CorTec aims to develop innovative implantable technology for stroke rehabilitation, enabling new therapies and devices while targeting market approval and $250M in sales by 2030.
NAO.VNS: A New Personalized Neural Stimulation Therapy For Drug-resistant Epilepsy
NAO.VNS is an innovative implantable vagus nerve stimulator using optical fibers to enhance treatment for drug-resistant epilepsy, enabling personalized therapy and remote monitoring, with market approval expected by 2028.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
AEGEUS - A Novel EEG Ultrasound Device for Functional Brain Imaging and NeurostimulationDevelop a novel wearable device combining ultrasound imaging and EEG for enhanced diagnosis and treatment of neurological disorders, aiming for improved patient outcomes and research advancements. | EIC Pathfinder | € 2.998.988 | 2023 | Details |
Epilepsy Treatment Using Neuromodulation by Non-Invasive Temporal Interference StimulationThe EMUNITI project aims to develop a non-invasive, personalized brain stimulation device using temporal interference to diagnose and treat epilepsy, enhancing patient care and outcomes. | ERC Consolid... | € 1.996.925 | 2023 | Details |
EpiGrid: Soft and flexible high density electrode grids for epilepsy surgeryThe project aims to develop and test flexible, high-density electrode grids for improved delineation of epileptogenic tissue during epilepsy surgery, enhancing success rates and treatment outcomes. | ERC Proof of... | € 150.000 | 2023 | Details |
Minimally invasive and closed-loop ultrasound neuromodulation and recording for the treatment of focal epilepsyThis project aims to develop a minimally invasive, closed-loop ultrasound neuromodulation system for treating refractory epilepsy, optimizing protocols through a comprehensive computational framework. | ERC Starting... | € 1.499.575 | 2025 | Details |
S4E-platform: Simulaties en Signaaldetectie voor EpilepsieHet project ontwikkelt een AI-platform (S4E) voor het voorspellen van epilepsiesubtypes via hersensimulaties en fNIRS, om diagnostiek en behandeling te verbeteren. | Mkb-innovati... | € 331.450 | 2023 | Details |
AEGEUS - A Novel EEG Ultrasound Device for Functional Brain Imaging and Neurostimulation
Develop a novel wearable device combining ultrasound imaging and EEG for enhanced diagnosis and treatment of neurological disorders, aiming for improved patient outcomes and research advancements.
Epilepsy Treatment Using Neuromodulation by Non-Invasive Temporal Interference Stimulation
The EMUNITI project aims to develop a non-invasive, personalized brain stimulation device using temporal interference to diagnose and treat epilepsy, enhancing patient care and outcomes.
EpiGrid: Soft and flexible high density electrode grids for epilepsy surgery
The project aims to develop and test flexible, high-density electrode grids for improved delineation of epileptogenic tissue during epilepsy surgery, enhancing success rates and treatment outcomes.
Minimally invasive and closed-loop ultrasound neuromodulation and recording for the treatment of focal epilepsy
This project aims to develop a minimally invasive, closed-loop ultrasound neuromodulation system for treating refractory epilepsy, optimizing protocols through a comprehensive computational framework.
S4E-platform: Simulaties en Signaaldetectie voor Epilepsie
Het project ontwikkelt een AI-platform (S4E) voor het voorspellen van epilepsiesubtypes via hersensimulaties en fNIRS, om diagnostiek en behandeling te verbeteren.