SubsidieMeestersDISCOVERING HOW PLANTS SENSE WATER STRESS
This project aims to uncover how plants sense water availability using innovative genetic and imaging techniques to enhance climate-resilient crop design for global food security.
Projectdetails
Introduction
Water stress is an increasing problem for global agriculture given the impact of climate change. Despite the fundamental importance of water, exactly how plants sense its availability remains unknown. This new knowledge is vital for designing more climate-resilient crops, yet currently remains a critical gap in scientific understanding.
Project Synergy
Our unique synergy is ideal to take on this ambitious project and discover how plants sense water after identifying membrane proteins from a proof-of-principle multi-targeted genetic screen designed to reveal components of the water-sensing (hydrosensing) machinery.
Hypothesis
We hypothesize that changes in plant hydraulic fluxes driven by transient water stress are sensed by a specialised cell type termed phloem companion cells, which controls the synthesis and release of the abiotic stress signal ABA.
Mechanism of ABA Release
Release of ABA by water stress is triggered by perturbations in plasma membrane-cell wall contact sensed by kinases like THESEUS1 (THE1) and additional missing components, which we will identify using our custom multi-targeted CRISPR libraries. Our discoveries will unlock the mechanism enabling the sensing of the most important molecule on the planet, WATER, in the most abundant lifeform biomass-wise, PLANTS.
Interdisciplinary Strategy
Solving how plants sense water demands a highly interdisciplinary strategy that goes beyond the cutting edge by pioneering the development of innovative genome editing, functional imaging, and structural biology approaches.
Partnership and Goals
The breadth and depth of capabilities and expertise to undertake this strategy necessitate a synergistic partnership between world-leading groups to go beyond the current state of the art. By pursuing this high-risk/high-gain strategy, our project promises to reveal common design principles that underpin the core mechanism(s) for water stress signalling in plants.
Importance of New Knowledge
This new knowledge is crucial for international efforts to design climate-resilient crops and underpin global food security.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 9.780.769 |
| Totale projectbegroting | € 9.780.769 |
Tijdlijn
| Startdatum | 1-5-2024 |
| Einddatum | 30-4-2029 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- TEL AVIV UNIVERSITYpenvoerder
- UNIVERSITAET REGENSBURG
- NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
- THE UNIVERSITY OF NOTTINGHAM
Land(en)
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