SubsidieMeestersUnravelling the epigenetic mechanisms underlying nutritional programming for sustainable aquaculture
EPIAQUA aims to explore the epigenetic effects of early nutritional interventions in Nile Tilapia to enhance sustainable aquafeeds and improve aquaculture efficiency and health.
Projectdetails
Introduction
Aquaculture supplies half of the fish consumed by humans, being the fastest growing food production sector worldwide. Reducing the use of fishery products in aquafeed by replacing them with more sustainable ingredients is a must to reach sustainability and meet future global food needs.
Nutritional Programming
In this sense, nutritional programming is a promising strategy with potential to increase production efficiency and fish health while minimizing environmental impact. Epigenetics is thought to be responsible for the beneficial effects of early nutritional intervention. However, the mechanisms by which different types of nutritional interventions induce epigenetic modifications, and which ones they induce, is largely unknown.
Project Overview
EPIAQUA is an innovative and timely project that will unravel the multi-layered epigenetic entanglement underlying nutritional programming and its transgenerational inheritance, using Nile Tilapia (Oreochromis niloticus) as a model. This project aims to pave the way for advances in the use of sustainable aquafeeds.
Specific Goals
Specific goals of the EPIAQUA project are:
- To elucidate the cause-effect relationship of carbohydrate content and dietary fatty acids early intervention on the multi-layered epigenome.
- To generate a better mechanistic understanding of the phenotypic changes induced by nutritional early intervention.
- To demonstrate the presence of epigenetic marks transgenerationally inherited and characterize the mechanisms underlying it.
Hypothesis and Impact
The new hypothesis that lncRNAs play a key role in the transmission and long-lasting effects of nutritionally mediated phenotypes is central to this proposal. This is one of its ground-breaking elements and has major translational impacts.
Expected Outcomes
Moreover, EPIAQUA outcomes will provide novel mechanistic insights into the role of epigenetics in nutritional programming. The project will identify novel epigenetic markers involved in tailoring metabolic pathways for better use of sustainable aquafeeds. This, in turn, will drive changes in husbandry protocols and improve aquaculture sustainability.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 1.500.000 |
| Totale projectbegroting | € 1.500.067 |
Tijdlijn
| Startdatum | 1-1-2024 |
| Einddatum | 31-12-2028 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- UNIVERSIDAD DE LA LAGUNApenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Feasibility of a multi-panel of epigenetic markers of fish growthEPISELECT aims to enhance Nile tilapia growth through a multi-panel assessment of epigenetic markers, improving breeding programs for greater sustainability and profitability in aquaculture. | ERC Proof of... | € 150.000 | 2023 | Details |
Antiviral Proteins Applied as Therapeutics in AquacultureThis project aims to validate antiviral proteins from rainbow trout to develop a new therapeutic solution that reduces viral infections and economic losses in aquaculture. | ERC Proof of... | € 150.000 | 2022 | Details |
Deciphering the newly discovered branchial cavity immune surveillance system to protect fish against infectious diseases in aquaculture.This project aims to characterize the fish branchial cavity immune system using zebrafish to enhance aquaculture disease management and vaccine development, potentially benefiting human health. | ERC Starting... | € 2.499.205 | 2025 | Details |
Unravelling specificity of epi-metabolic regulation in mouse developmentThis project aims to uncover how metabolic changes influence epigenetic outcomes during mouse embryo implantation, using multi-omic approaches and mechanistic experiments to explore regulatory processes. | ERC Starting... | € 1.500.000 | 2023 | Details |
Genetic Design of Biological Time in FishThis project aims to develop genetic tools to study the pace of life in vertebrates using turquoise killifish, enhancing understanding of aging and its regulation for potential medical and aquaculture applications. | ERC Starting... | € 1.500.000 | 2023 | Details |
Feasibility of a multi-panel of epigenetic markers of fish growth
EPISELECT aims to enhance Nile tilapia growth through a multi-panel assessment of epigenetic markers, improving breeding programs for greater sustainability and profitability in aquaculture.
Antiviral Proteins Applied as Therapeutics in Aquaculture
This project aims to validate antiviral proteins from rainbow trout to develop a new therapeutic solution that reduces viral infections and economic losses in aquaculture.
Deciphering the newly discovered branchial cavity immune surveillance system to protect fish against infectious diseases in aquaculture.
This project aims to characterize the fish branchial cavity immune system using zebrafish to enhance aquaculture disease management and vaccine development, potentially benefiting human health.
Unravelling specificity of epi-metabolic regulation in mouse development
This project aims to uncover how metabolic changes influence epigenetic outcomes during mouse embryo implantation, using multi-omic approaches and mechanistic experiments to explore regulatory processes.
Genetic Design of Biological Time in Fish
This project aims to develop genetic tools to study the pace of life in vertebrates using turquoise killifish, enhancing understanding of aging and its regulation for potential medical and aquaculture applications.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Synthetic proteins for sustainable animal feedingSYNFEED aims to revolutionize animal feeding by developing sustainable, digestible proteins through precision nutrition and biosynthesis, reducing environmental impact and EU dependency on imports. | EIC Pathfinder | € 3.079.962 | 2025 | Details |
Ontwikkeling AI AquacultureHet project ontwikkelt een betaalbaar AI video-platform voor de monitoring van kweekvis, met als doel betere viskwaliteit, dierenwelzijn en economische groei in de aquacultuur. | Mkb-innovati... | € 171.045 | 2023 | Details |
From salmon sludge and manure to fertiliser: a circular economy around land-based salmon farmingTerraforming LIFE aims to develop an Integrated Agriculture Aquaculture system that optimizes water recycling and bio-fertilizer production, enhancing sustainability and reducing CO2 emissions. | LIFE Standar... | € 6.259.911 | 2023 | Details |
Ontwikkeling AI AquacultureHet project ontwikkelt een AI-platform voor geautomatiseerde monitoring en analyse van kweekvis, ter verbetering van dierenwelzijn en voedselkwaliteit. | Mkb-innovati... | € 171.045 | 2023 | Details |
FinnovationHet project ontwikkelt duurzame technieken voor het kweken van vis uit cellen om overbevissing te verminderen en gezonde alternatieven voor consumptie te bieden. | Mkb-innovati... | € 20.000 | 2021 | Details |
Synthetic proteins for sustainable animal feeding
SYNFEED aims to revolutionize animal feeding by developing sustainable, digestible proteins through precision nutrition and biosynthesis, reducing environmental impact and EU dependency on imports.
Ontwikkeling AI Aquaculture
Het project ontwikkelt een betaalbaar AI video-platform voor de monitoring van kweekvis, met als doel betere viskwaliteit, dierenwelzijn en economische groei in de aquacultuur.
From salmon sludge and manure to fertiliser: a circular economy around land-based salmon farming
Terraforming LIFE aims to develop an Integrated Agriculture Aquaculture system that optimizes water recycling and bio-fertilizer production, enhancing sustainability and reducing CO2 emissions.
Ontwikkeling AI Aquaculture
Het project ontwikkelt een AI-platform voor geautomatiseerde monitoring en analyse van kweekvis, ter verbetering van dierenwelzijn en voedselkwaliteit.
Finnovation
Het project ontwikkelt duurzame technieken voor het kweken van vis uit cellen om overbevissing te verminderen en gezonde alternatieven voor consumptie te bieden.