Robotic and Electrical Stimulation Platform for Integral Neuromuscular Enhancement

Introduction

RE-SPINE develops a real-time neuro-robotic platform for lower limb rehabilitation. Motor recovery following neuromuscular injuries is often sub-optimal. A key barrier hampering progress is that current neurorehabilitation robots interact with the human with limited knowledge of their effect on critical neuromuscular targets.

Proposed Solution

RE-SPINE addresses this challenge by proposing a platform that integrates a stationary robotic ankle exoskeleton with a non-invasive spinal cord electrical stimulation system. This platform generates electrical and mechanical stimuli non-invasively, which are directed to spinal motor neurons and innervated muscle fibers, with precision not considered before.

Technology Integration

RE-SPINE combines non-invasive biosignal recording and numerical modeling to decode the cellular activity of spinal motor neurons, with the resulting mechanical forces generated by innervated muscle fibers.

1. Residual spinal motor neuron activity is translated into biomechanical force.
2. This force is subsequently used to enable volitional and continuous control of a stationary robotic ankle exoskeleton across a wide range of joint rotations, which could not be otherwise achieved without neuro-robotic support.

Spinal Cord Stimulation

Concurrently, decoded spinal motor neuron activity is used to command spinal cord electrical stimulation patterns that:

• Modulate spinal excitability
• Enhance neuronal synchronization
• Ultimately improve volitional control of the own leg

Long-term Benefits

Over time, the integrated effects of neuro-controlled electrical and mechanical stimulation promote positive neuroplastic changes, which are required for gaining integral motor recovery after injury. This approach has the potential to disrupt current robotic systems for rehabilitation.