reGeneRative bone Implant for the treatment of hip dysPlasia
GRIP aims to revolutionize hip dysplasia treatment with personalized, 3D-printed regenerative bone implants, enhancing integration and reducing invasiveness compared to current methods.
Projectdetails
Introduction
GRIP develops a personalised, 3D-printed regenerative bone implant as a treatment for hip instability (hip dysplasia) and its commercialisation strategy. Osteoarthritis (OA) of the hip is a painful and debilitating condition, and hip dysplasia is one of the two main causes.
Current Surgical Methods
The currently most common surgical methods to correct the dysplasia involve:
- The re-alignment of the hip socket (osteotomy)
- The insertion of a bone graft to enlarge the socket (shelf arthroplasty)
While the osteotomy is invasive, the shelf arthroplasty requires donor tissue. In addition, both procedures only have limited success rates.
GRIP Implants
GRIP implants overcome the current shortcomings of these methods and provide a novel personalized implant to treat hip dysplasia. GRIP will provide patients and surgeons with an easy-to-use, one-step, and cost-effective regenerative device, therefore overcoming the significant drawbacks of current treatments for hip dysplasia.
Fabrication Process
The GRIP implants will be precisely fabricated from a flexible bone-inducing biomaterial through a process both developed and established within the ERC-CoG “3D-JOINT” project. This will ensure a perfect fit, resulting in optimal integration and durable restoration of the hip socket, as well as obviating the need for complex and invasive osteotomy surgeries.
Impact on Treatment
GRIP implants will revolutionise the treatment of hip dysplasia as they provide a stable, long-term, and regenerative solution that will fully integrate with the host bone tissue. Moreover, the regenerative nature will also make this a potential treatment option for younger (paediatric) patients.
Economic Value and Market Strategy
As GRIP will transform the treatment of hip dysplasia and improve the long-term health and well-being of both human and veterinary patients, the economic value and the route to the market for the GRIP technologies will be explored.
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 150.000 |
Totale projectbegroting | € 150.000 |
Tijdlijn
Startdatum | 1-8-2022 |
Einddatum | 31-1-2024 |
Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- UNIVERSITAIR MEDISCH CENTRUM UTRECHTpenvoerder
Land(en)
Geen landeninformatie beschikbaar
Vergelijkbare projecten binnen European Research Council
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
MANUNKIND: Determinants and Dynamics of Collaborative ExploitationThis project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery. | ERC STG | € 1.497.749 | 2022 | Details |
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressureThe UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance. | ERC STG | € 1.498.280 | 2022 | Details |
Uncovering the mechanisms of action of an antiviral bacteriumThis project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function. | ERC STG | € 1.500.000 | 2023 | Details |
The Ethics of Loneliness and SociabilityThis project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field. | ERC STG | € 1.025.860 | 2023 | Details |
MANUNKIND: Determinants and Dynamics of Collaborative Exploitation
This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressure
The UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance.
Uncovering the mechanisms of action of an antiviral bacterium
This project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function.
The Ethics of Loneliness and Sociability
This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
Vergelijkbare projecten uit andere regelingen
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
Modelling trajectories and mechanisms of childhood hip dysplasiaThe HIPSTAR project aims to identify and prevent hip dysplasia in children to reduce the risk of developing osteoarthritis in adulthood by studying growth patterns and causal factors. | ERC ADG | € 2.499.373 | 2023 | Details |
The Holy Grail in Bone regenerationGreenBone aims to revolutionize bone grafts with a synthetic Rattan wood-based implant that mimics natural bone, enhancing regeneration and targeting the spinal market by 2025. | EIC Accelerator | € 2.458.128 | 2022 | Details |
Gedigitaliseerde productie van gepersonaliseerde koker en liner voor onderbeenprothesesGyromotics en Jolutions ontwikkelen samen een gepersonaliseerde koker en liner voor amputees, met innovatieve productietechnieken die de productie-efficiëntie en zorgkwaliteit verbeteren. | MIT R&D Samenwerking | € 170.240 | 2022 | Details |
Meegroeiprothese: one size fits allGyromotics en MTPP ontwikkelen een verstelbare kinderonderbeenprothese van carboncomposieten die meegroeit met kinderen, om hun bewegingsvrijheid en sociale interactie te verbeteren. | MIT R&D Samenwerking | € 178.598 | 2020 | Details |
Modelling trajectories and mechanisms of childhood hip dysplasia
The HIPSTAR project aims to identify and prevent hip dysplasia in children to reduce the risk of developing osteoarthritis in adulthood by studying growth patterns and causal factors.
The Holy Grail in Bone regeneration
GreenBone aims to revolutionize bone grafts with a synthetic Rattan wood-based implant that mimics natural bone, enhancing regeneration and targeting the spinal market by 2025.
Gedigitaliseerde productie van gepersonaliseerde koker en liner voor onderbeenprotheses
Gyromotics en Jolutions ontwikkelen samen een gepersonaliseerde koker en liner voor amputees, met innovatieve productietechnieken die de productie-efficiëntie en zorgkwaliteit verbeteren.
Meegroeiprothese: one size fits all
Gyromotics en MTPP ontwikkelen een verstelbare kinderonderbeenprothese van carboncomposieten die meegroeit met kinderen, om hun bewegingsvrijheid en sociale interactie te verbeteren.