SubsidieMeestersNanowire device for single virus delivery and sensing in vacuum
VIR-Quantify aims to develop a novel technology for rapid, sensitive airborne virus detection and infectivity assessment, enhancing public health response and enabling commercialization.
Projectdetails
Introduction
Airborne viruses causing respiratory diseases represent a major global health threat, being viruses with RNA genomes from animal reservoirs highly likely to cause further public health emergencies in the future.
Project Overview
VIR-Quantify aims to provide proof of concept for a technology capable of highly sensitive, fast, and untargeted airborne virus detection with infectivity assessment, providing a comparative advantage in the competitive landscape. VIR-Quantify builds upon an unprecedented application of NMS sensors to the field of airborne viral particles detection (methodology developed and patented by the PI in the framework of a previous ERC CoG).
Methodology
VIR-Quantify proposes the use of ionic liquids to preserve the virus structure, together with nanowire sensors that allow mass and stiffness measurements for identification and infectivity studies of the pathogens.
Innovative Solutions
The innovative solution lies in two fronts:
- An unprecedented capability to measure with high throughput (30 particles/minute) the stiffness of intact viruses to infer their infectivity potential, which is not reachable by other techniques.
- The capability to count and characterize all the viral particles present in the liquid sample without loss of bioanalytes during the measurements.
Goals
VIR-Quantify aims to exploit the novel technology for on-site identification and quantification of airborne viral particles and validate the innovation potential of such technological tool for commercialization by developing a market entry strategy built upon IPR consolidation and spin-off set-up.
Expected Outcomes
This will lead to high-gain, disruptive outcomes in the form of unprecedented mechanistic understanding for detecting the quick spread of airborne viral particles with great socioeconomic benefits visible at three levels:
- Fueling industrial innovation and economic growth in a game-changing sector (preventive medicine).
- Reducing healthcare costs worldwide, thus enabling more resilient and efficient health systems.
- Improving human welfare.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-7-2024 |
| Einddatum | 31-12-2025 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICASpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
MANUNKIND: Determinants and Dynamics of Collaborative ExploitationThis project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery. | ERC STG | € 1.497.749 | 2022 | Details |
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressureThe UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance. | ERC STG | € 1.498.280 | 2022 | Details |
Uncovering the mechanisms of action of an antiviral bacteriumThis project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function. | ERC STG | € 1.500.000 | 2023 | Details |
The Ethics of Loneliness and SociabilityThis project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field. | ERC STG | € 1.025.860 | 2023 | Details |
MANUNKIND: Determinants and Dynamics of Collaborative Exploitation
This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressure
The UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance.
Uncovering the mechanisms of action of an antiviral bacterium
This project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function.
The Ethics of Loneliness and Sociability
This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Dynamics and heterogeneity of early viral infectionThis project aims to enhance imaging technology to study early infection processes of negative-sense RNA viruses, focusing on RSV to understand viral propagation and inform therapeutic strategies. | ERC COG | € 2.000.000 | 2023 | Details |
Deciphering the nanobiophysics of virus-host interactions in 3D cellular systemsThis project aims to elucidate virus-host interactions during entry in 3D environments using advanced nanotechniques, potentially leading to new antiviral drug discoveries. | ERC COG | € 2.867.346 | 2023 | Details |
Vibrations of viral particles scatter lightThe VIRUSong project aims to develop a novel technology for rapid and sensitive identification of viral particles using vibrational spectroscopy and nanoparticle resonators, enhanced by AI analysis. | EIC Pathfinder | € 6.069.304 | 2023 | Details |
Optimalisatie van afvangstrendementen voor lucht-gedragen fijnstof en ziekteverwekkersENS Technology ontwikkelt een prototype van de 'Positieve Ionisatie Technologie' om de afvang van schadelijke luchtdeeltjes en micro-organismen te optimaliseren voor betere luchtkwaliteit en gezondheidsbescherming. | MIT Haalbaarheid | € 20.000 | 2022 | Details |
Dynamics and heterogeneity of early viral infection
This project aims to enhance imaging technology to study early infection processes of negative-sense RNA viruses, focusing on RSV to understand viral propagation and inform therapeutic strategies.
Deciphering the nanobiophysics of virus-host interactions in 3D cellular systems
This project aims to elucidate virus-host interactions during entry in 3D environments using advanced nanotechniques, potentially leading to new antiviral drug discoveries.
Vibrations of viral particles scatter light
The VIRUSong project aims to develop a novel technology for rapid and sensitive identification of viral particles using vibrational spectroscopy and nanoparticle resonators, enhanced by AI analysis.
Optimalisatie van afvangstrendementen voor lucht-gedragen fijnstof en ziekteverwekkers
ENS Technology ontwikkelt een prototype van de 'Positieve Ionisatie Technologie' om de afvang van schadelijke luchtdeeltjes en micro-organismen te optimaliseren voor betere luchtkwaliteit en gezondheidsbescherming.