NONLINEAR DYNAMICS OF FLUCTUATING TWO-DIMENSIONAL MATERIALS IN ACTION
NCANTO aims to harness nonlinear dynamics in 2D materials to create highly-sensitive nanomechanical devices for improved frequency stability and single-cell sensing in drug development.
Projectdetails
Introduction
Two-dimensional (2D) materials are unique platforms for studying fundamental science. They bridge the gap between the world of atomic scale dynamics and the world of macroscopic mechanical vibrations. Owing to their small size, they can enable exploration of research areas that lie at the forefront of classical and quantum technologies.
Challenges
However, their noisy and nonlinear nature limits their performance. This combination of fluctuations and nonlinearities brings to light a new regime of mechanics that has remained largely untapped. If well-understood, this regime can open a wide range of trajectories in high-performance sensing and lab-on-a-chip devices.
Project Goals
NCANTO aims at elucidating the strong interplay between nonlinearities and noise at the atomic scale. The project will leverage the acquired knowledge to engineer 2D nanomechanical devices that:
- Offer extreme frequency stability.
- Enable robust and highly-sensitive single-cell sensing.
Research Approach
To realize this vision, I will explore the influence of a range of nonlinear dynamic phenomena on two important noise sources, namely:
- Frequency fluctuations.
- Biological noise.
My approach will combine state-of-the-art modelling and experimental techniques to deliver novel designs that utilize nonlinear dynamic phenomena at their core.
Expected Outcomes
These designs will:
- Quench frequency noise in 2D resonators for breakthrough performance.
- Enhance biological rhythms at the single-cell level for robust drug screening.
By linking stochastic dynamics, nanomechanics, nonlinear dynamics, and structural optimization, I will develop a multidisciplinary research area that will enable a ground-breaking leap forward in the utilization of 2D materials as nonlinear sensors in frequency-based metrology and bio-health.
Conclusion
NCANTO will thus not only herald new frontiers in nanomechanics but will also open new routes towards engineering nanotools for rapid screening tests in drug development and personalized medicine.
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 1.999.021 |
Totale projectbegroting | € 1.999.021 |
Tijdlijn
Startdatum | 1-6-2024 |
Einddatum | 31-5-2029 |
Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- TECHNISCHE UNIVERSITEIT DELFTpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
MANUNKIND: Determinants and Dynamics of Collaborative ExploitationThis project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery. | ERC STG | € 1.497.749 | 2022 | Details |
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressureThe UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance. | ERC STG | € 1.498.280 | 2022 | Details |
Uncovering the mechanisms of action of an antiviral bacteriumThis project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function. | ERC STG | € 1.500.000 | 2023 | Details |
The Ethics of Loneliness and SociabilityThis project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field. | ERC STG | € 1.025.860 | 2023 | Details |
MANUNKIND: Determinants and Dynamics of Collaborative Exploitation
This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressure
The UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance.
Uncovering the mechanisms of action of an antiviral bacterium
This project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function.
The Ethics of Loneliness and Sociability
This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
Vergelijkbare projecten uit andere regelingen
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
Nanoprobes for Nonequilibrium Driven SystemsThis project aims to develop fluorescent nanosensors to quantify energy dissipation in nonequilibrium biological systems, enhancing understanding of molecular motors and thermodynamic constraints. | ERC STG | € 1.500.000 | 2022 | Details |
Band-resolved imaging and nonlinear optical control of currents in topological materialsThis project aims to develop nonlinear coherent control of photocurrents in topological materials using time-resolved ARPES to enhance understanding and application of their unique optical properties. | ERC STG | € 2.316.250 | 2023 | Details |
Three Dimensional Quantum NanomaterialsThis project aims to explore the physics of 3D quantum nanomaterials through advanced experimental techniques, enhancing understanding and applications in technology and fundamental research. | ERC STG | € 1.500.000 | 2024 | Details |
The Spectrum of Fluctuations in Living MatterThis project aims to develop a theoretical framework for predicting active fluctuations in living matter by analyzing subcellular and tissue-scale dynamics, enhancing our understanding of biological processes. | ERC STG | € 1.499.575 | 2024 | Details |
Nanoprobes for Nonequilibrium Driven Systems
This project aims to develop fluorescent nanosensors to quantify energy dissipation in nonequilibrium biological systems, enhancing understanding of molecular motors and thermodynamic constraints.
Band-resolved imaging and nonlinear optical control of currents in topological materials
This project aims to develop nonlinear coherent control of photocurrents in topological materials using time-resolved ARPES to enhance understanding and application of their unique optical properties.
Three Dimensional Quantum Nanomaterials
This project aims to explore the physics of 3D quantum nanomaterials through advanced experimental techniques, enhancing understanding and applications in technology and fundamental research.
The Spectrum of Fluctuations in Living Matter
This project aims to develop a theoretical framework for predicting active fluctuations in living matter by analyzing subcellular and tissue-scale dynamics, enhancing our understanding of biological processes.