SubsidieMeestersAdvancing stroke care with cutting-edge ultrasound biomarkers for Neurocritical Care
Resolve Stroke aims to enhance ultrasound imaging with the SYLVER system to improve stroke diagnosis and management through innovative biomarkers, making timely detection more accessible and effective.
Projectdetails
Introduction
Today, the lack of effective imaging kills. Early diagnosis can cure most deadly diseases, and stroke is a prime example. With one in four adults likely to experience a stroke, timely detection is crucial.
Current Challenges
Unfortunately, current imaging tools fall short for bedside diagnosis, wasting valuable time both in ambulances and at the patient’s bedside. To implement widespread screening and advanced therapies, we need to:
- Increase the accessibility of CT scans and MRIs by 100-fold.
- Drastically improve their limitations.
Proposed Solution
The solution lies in enhancing ultrasound, a portable and accessible imaging modality.
Our Innovation
At Resolve Stroke, we are unlocking ultrasound's full potential with SYLVER, our innovative point-of-care ultrasound system powered by Software-Based Ultrasound technologies.
Technology Features
- SYLVER harnesses 100% of raw ultrasound data to deliver life-saving insights through advanced 3D algorithms and imaging.
- By combining ultrasound with advanced post-processing algorithms, SYLVER expands the boundaries of what ultrasound can achieve.
Applications
Key opinion leaders are already identifying new critical applications for our technologies, extending beyond neurology into fields like:
- Oncology, to monitor tumor aggressiveness.
- Transplant vascularization.
Novel Biomarkers
With access to this new ultrasound data, novel ultrasound-based biomarkers, such as:
- RS-LVO (Large Vessel Occlusion detection)
- RS-USP (Ultrasound Perfusion Score)
have the potential to revolutionize stroke management and brain care. These biomarkers offer critical, quantitative insights comparable to those obtained through CT scans, but with the added benefits of the ultrasound modality.
EIC Support
EIC support will enable us to develop, validate, and integrate RS-LVO and RS-USP into the SYLVER system. This includes validation in both laboratory and clinical settings to confirm their efficacy in real-world applications, at the patient’s bedside.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.493.436 |
| Totale projectbegroting | € 2.493.436 |
Tijdlijn
| Startdatum | 1-6-2025 |
| Einddatum | 31-5-2027 |
| Subsidiejaar | 2025 |
Partners & Locaties
Projectpartners
- RESOLVE STROKE SASpenvoerder
Land(en)
Vergelijkbare projecten binnen EIC Transition
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Very High Energy Electrons Beam for RadiotherapyeBeam4Therapy aims to revolutionize cancer treatment by developing compact, cost-effective VHEE radiotherapy using laser plasma accelerators to improve patient outcomes and reduce side effects. | EIC Transition | € 2.477.043 | 2022 | Details |
High-throughput hyperspectral imaging across the VIS-SWIR spectrum in a single deviceThe HYPERIA project aims to develop a novel hyperspectral imaging camera using Fourier Transform interferometry for enhanced sensitivity and wavelength range, targeting applications in food safety and waste separation. | EIC Transition | € 1.500.000 | 2022 | Details |
Therapeutic Antisense Oligonucleotides Targeting NUMB Alternative Splicing in Lung AdenocarcinomaThis project aims to develop Antisense Oligonucleotides to correct pathological splicing of the NUMB gene in lung adenocarcinomas, improving treatment efficacy and paving the way for clinical trials. | EIC Transition | € 2.899.553 | 2022 | Details |
Photonic chip based high-throughput, multi-modal and scalable optical nanoscopy platformNanoVision aims to revolutionize optical nanoscopy with an affordable, compact, and high-throughput photonic-chip solution, enhancing accessibility and flexibility for research and clinical labs. | EIC Transition | € 2.489.571 | 2022 | Details |
Very High Energy Electrons Beam for Radiotherapy
eBeam4Therapy aims to revolutionize cancer treatment by developing compact, cost-effective VHEE radiotherapy using laser plasma accelerators to improve patient outcomes and reduce side effects.
High-throughput hyperspectral imaging across the VIS-SWIR spectrum in a single device
The HYPERIA project aims to develop a novel hyperspectral imaging camera using Fourier Transform interferometry for enhanced sensitivity and wavelength range, targeting applications in food safety and waste separation.
Therapeutic Antisense Oligonucleotides Targeting NUMB Alternative Splicing in Lung Adenocarcinoma
This project aims to develop Antisense Oligonucleotides to correct pathological splicing of the NUMB gene in lung adenocarcinomas, improving treatment efficacy and paving the way for clinical trials.
Photonic chip based high-throughput, multi-modal and scalable optical nanoscopy platform
NanoVision aims to revolutionize optical nanoscopy with an affordable, compact, and high-throughput photonic-chip solution, enhancing accessibility and flexibility for research and clinical labs.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
QSM in plaque vulnerability diagnosis – a software tool for early clinical assessmentVASCOLL aims to develop a non-invasive software tool using QSM technology to assess carotid plaque vulnerability, enabling early diagnosis and optimized treatment to reduce surgery needs and costs. | ERC POC | € 150.000 | 2022 | Details |
Remote whole-brain functional microscopy of the vascular system: a paradigm shift for the monitoring and treatment of small vessel diseasesThe project aims to revolutionize neuroimaging by developing functional Ultrasound Localization Microscopy (fULM) for high-resolution monitoring of brain vasculature and function, enhancing disease diagnosis and treatment evaluation. | EIC Pathfinder | € 3.946.172 | 2022 | Details |
Monitoring of stroke patients with 3D ultrasound localization microscopyThe ERC POC StrokeMonitor project aims to validate a portable super-resolution ultrasound device for monitoring delayed cerebral ischemia in stroke patients, enhancing neuroimaging accessibility and accuracy. | ERC POC | € 150.000 | 2023 | Details |
Cloud-native ultrasound imagingCloudSound aims to revolutionize ultrasound imaging by leveraging cloud computing for high-quality, affordable, and accessible medical imaging through a closed-loop, goal-directed approach. | ERC POC | € 150.000 | 2024 | Details |
QSM in plaque vulnerability diagnosis – a software tool for early clinical assessment
VASCOLL aims to develop a non-invasive software tool using QSM technology to assess carotid plaque vulnerability, enabling early diagnosis and optimized treatment to reduce surgery needs and costs.
Remote whole-brain functional microscopy of the vascular system: a paradigm shift for the monitoring and treatment of small vessel diseases
The project aims to revolutionize neuroimaging by developing functional Ultrasound Localization Microscopy (fULM) for high-resolution monitoring of brain vasculature and function, enhancing disease diagnosis and treatment evaluation.
Monitoring of stroke patients with 3D ultrasound localization microscopy
The ERC POC StrokeMonitor project aims to validate a portable super-resolution ultrasound device for monitoring delayed cerebral ischemia in stroke patients, enhancing neuroimaging accessibility and accuracy.
Cloud-native ultrasound imaging
CloudSound aims to revolutionize ultrasound imaging by leveraging cloud computing for high-quality, affordable, and accessible medical imaging through a closed-loop, goal-directed approach.