SubsidieMeestersA first-in-class therapy for intestinal malabsorption in premature newborns
ELGN-GI is a pioneering drug aimed at accelerating gut maturation in preterm infants, reducing reliance on parenteral nutrition and lowering risks of infections and complications.
Projectdetails
Introduction
Around 10% of babies are born preterm, and premature birth is the first cause of newborn deaths. Preterm infants are born with an underdeveloped gastrointestinal (GI) tract, causing intestinal malabsorption.
Importance of Nutrition
At the first weeks of life, adequate nutrition is critical for brain and vital organ development. Therefore, infants are placed on central line nutrition until their GI is capable of absorbing sufficient nutrition.
Risks of Central Line Nutrition
However, central line nutrition is inadequate for critical growth and poses life-threatening risks. Thus, a fast transition to oral independence is the goal for improving outcomes.
ELGN-GI Drug
ELGN-GI is the first drug for stimulating gut maturation for rapid transition to oral nutrition.
Benefits of ELGN-GI
It is safe and has demonstrated the following benefits:
- Reduces dependency on Parenteral Nutrition by 4 days.
- Decreases hospitalization time in high-level NICU by approximately 7 days.
- Contributes to a 40% reduction of life-threatening infections and Necrotizing Enterocolitis.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.359.000 |
| Totale projectbegroting | € 3.370.000 |
Tijdlijn
| Startdatum | 1-11-2022 |
| Einddatum | 31-10-2024 |
| Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- ELGAN PHARMA LTD.penvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
A new cardioprotective drug for acute treatment of myocardial infarctionResoTher aims to validate RTP-026, an immunomodulating therapy, to reduce heart damage and HF risk post-myocardial infarction through Phase II clinical studies. | EIC Accelerator | € 2.499.999 | 2024 | Details |
Clear, scalable and scientific framework to measure terrestrial biodiversity3Bee leverages IoT, wildlife monitoring, and satellite data to measure and regenerate biodiversity, generating certified Biodiversity Credits for corporations to enhance ESG reporting and brand value. | EIC Accelerator | € 2.252.714 | 2024 | Details |
Novel and Scalable microbial products for REgenerative agricultureN-Spire aims to revolutionize agriculture by creating a sustainable bioactive fertilizer through innovative manufacturing techniques, enhancing soil health and reducing chemical dependency. | EIC Accelerator | € 2.499.999 | 2024 | Details |
Quantum-based Randomness Processing Units (RPUs) for High-Performance Computation and Data SecurityQuside's Randomness Processing Unit (RPU) accelerates stochastic HPC and PQ cryptography by optimizing random workloads, enhancing efficiency and performance across various sectors. | EIC Accelerator | € 2.499.999 | 2024 | Details |
A new cardioprotective drug for acute treatment of myocardial infarction
ResoTher aims to validate RTP-026, an immunomodulating therapy, to reduce heart damage and HF risk post-myocardial infarction through Phase II clinical studies.
Clear, scalable and scientific framework to measure terrestrial biodiversity
3Bee leverages IoT, wildlife monitoring, and satellite data to measure and regenerate biodiversity, generating certified Biodiversity Credits for corporations to enhance ESG reporting and brand value.
Novel and Scalable microbial products for REgenerative agriculture
N-Spire aims to revolutionize agriculture by creating a sustainable bioactive fertilizer through innovative manufacturing techniques, enhancing soil health and reducing chemical dependency.
Quantum-based Randomness Processing Units (RPUs) for High-Performance Computation and Data Security
Quside's Randomness Processing Unit (RPU) accelerates stochastic HPC and PQ cryptography by optimizing random workloads, enhancing efficiency and performance across various sectors.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Preterm Brain-Oxygenation and Metabolic EU-Sensing: Feed the BrainPrometeus aims to personalize nutrition for premature neonates in NICUs through real-time adjustments of glucose and nutrients based on brain needs, reducing the risk of neurodevelopmental disabilities. | EIC Pathfinder | € 3.554.156 | 2023 | Details |
Artificial Placenta (ArtPlac) - Miniaturized Integrated Lung and Kidney Support for Critically Ill NewbornsThe ArtPlac project aims to revolutionize newborn care by developing a compact artificial placenta to reduce neonatal deaths and long-term complications through less invasive support. | EIC Pathfinder | € 4.229.608 | 2023 | Details |
Postbiotic Restoration Of the Metabolome Of MomsPRO-MOM aims to develop a postbiotic supplement to restore maternal-neonatal microbiota and mitigate behavioral disturbances in offspring following antibiotic use during pregnancy and breastfeeding. | ERC POC | € 150.000 | 2024 | Details |
Thuisbehandeling en monitoring van geelzucht bij pas- en vroeggeborenen: User flowHet project richt zich op het ontwikkelen van effectieve behandelingen voor geelzucht bij pasgeborenen, met speciale aandacht voor vroeggeborenen om neurologische schade te voorkomen. | MIT Haalbaarheid | € 20.000 | 2022 | Details |
Preterm Brain-Oxygenation and Metabolic EU-Sensing: Feed the Brain
Prometeus aims to personalize nutrition for premature neonates in NICUs through real-time adjustments of glucose and nutrients based on brain needs, reducing the risk of neurodevelopmental disabilities.
Artificial Placenta (ArtPlac) - Miniaturized Integrated Lung and Kidney Support for Critically Ill Newborns
The ArtPlac project aims to revolutionize newborn care by developing a compact artificial placenta to reduce neonatal deaths and long-term complications through less invasive support.
Postbiotic Restoration Of the Metabolome Of Moms
PRO-MOM aims to develop a postbiotic supplement to restore maternal-neonatal microbiota and mitigate behavioral disturbances in offspring following antibiotic use during pregnancy and breastfeeding.
Thuisbehandeling en monitoring van geelzucht bij pas- en vroeggeborenen: User flow
Het project richt zich op het ontwikkelen van effectieve behandelingen voor geelzucht bij pasgeborenen, met speciale aandacht voor vroeggeborenen om neurologische schade te voorkomen.