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Precision tissue biobanking made easy

The project aims to develop and validate an automated tissue harvesting system, ARTS, to enhance biobanking efficiency, quality, and sustainability for improved disease research and diagnostics.

Subsidie
€ 150.000
2023

Projectdetails

Introduction

Large scale biobanks are essential to meet the world-wide demand for high quality tissues to understand the development and progression of disease, or discover and validate novel biomarkers. Current biobanking protocols for harvesting and processing tissue are manual and therefore rely on experienced and costly on-site personnel.

Vision for Improvement

Imagine the possibilities of scientific discoveries in personalized diagnostics, prognostics, and treatment if high-quality tissues could be made available from several hospitals using streamlined, harmonized, and automated biobanking protocols. These protocols would also allow for maximal utilization of this precious material.

Proposed Solution

In this PoC, we propose a shift from a human-centered to a semi- or fully automated tissue harvesting and processing protocol. Specifically, we propose to develop further, test, and validate (from TRL4 to TRL7) an Augmented Reality enhanced and automated Tissue Sampler (ARTS).

Features of ARTS

The ARTS technology is:

  1. Cost-effective
  2. Simple to operate
  3. Allows for maximal tissue utilization

The ARTS prototype was developed within my ongoing ERC StG and already enables sub-samples to be selected from tissue based on invisible features such as diseased and non-diseased cells, addressing one of the general challenges of biobanking today.

Process Monitoring and Quality Assurance

In this PoC, we will include comprehensive process monitoring and sample tracking features such as:

  • Position
  • Temperature
  • Processing time

These features will allow automated sub-sampling while ensuring operator quality assurance with minimal hands-on time.

User Interface and Industry Readiness

We will also incorporate a tested user-friendly interface ready for industry and a potential spin-off company.

Benefits of ARTS

ARTS will allow biobanks to serve customers with specific and high-quality targeted sub-samples, which will enhance the value of the material through:

  • Increased reproducibility
  • Faster processing
  • More efficient utilization

In addition, ARTS will relieve financial burden and achieve more long-term sustainability for biobanks, which typically depend on public funding.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 150.000
Totale projectbegroting€ 150.000

Tijdlijn

Startdatum1-1-2023
Einddatum30-6-2024
Subsidiejaar2023

Partners & Locaties

Projectpartners

  • NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNUpenvoerder

Land(en)

Norway

Inhoudsopgave

European Research Council

Financiering tot €10 miljoen voor baanbrekend frontier-onderzoek via ERC-grants (Starting, Consolidator, Advanced, Synergy, Proof of Concept).

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