SubsidieMeestersImproving cancer therapy by identification of novel drug leads modulating transcription termination bridging molecular biology and therapeutic applications
The project aims to enhance cancer therapy by developing an automated screening platform to identify small molecule inhibitors that target transcription termination.
Projectdetails
Introduction
Our value proposition is improving cancer therapy by identification of novel anti-cancer candidate drug leads modulating transcription termination, bridging molecular cancer biology and therapeutic applications.
Methodology Development
We have developed a methodology to directly measure alterations in transcription termination.
Miniaturization and Automatization
Successfully, we subjected this methodology to miniaturization and automatization processes.
Funding Application
We are applying for funding to validate a screening platform to identify small molecule inhibitors of transcription termination.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-1-2026 |
| Einddatum | 30-6-2027 |
| Subsidiejaar | 2026 |
Partners & Locaties
Projectpartners
- UNIWERSYTET IM. ADAMA MICKIEWICZA WPOZNANIUpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
MANUNKIND: Determinants and Dynamics of Collaborative ExploitationThis project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery. | ERC STG | € 1.497.749 | 2022 | Details |
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MANUNKIND: Determinants and Dynamics of Collaborative Exploitation
This project aims to develop a game theoretic framework to analyze the psychological and strategic dynamics of collaborative exploitation, informing policies to combat modern slavery.
Elucidating the phenotypic convergence of proliferation reduction under growth-induced pressure
The UnderPressure project aims to investigate how mechanical constraints from 3D crowding affect cell proliferation and signaling in various organisms, with potential applications in reducing cancer chemoresistance.
The Ethics of Loneliness and Sociability
This project aims to develop a normative theory of loneliness by analyzing ethical responsibilities of individuals and societies to prevent and alleviate loneliness, establishing a new philosophical sub-field.
Uncovering the mechanisms of action of an antiviral bacterium
This project aims to uncover the mechanisms behind Wolbachia's antiviral protection in insects and develop tools for studying symbiont gene function.
Vergelijkbare projecten uit andere regelingen
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|---|---|---|---|---|
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