SubsidieMeestersMagnetic Resonance at the Scale of a Cell
The HyperCell project aims to revolutionize cell research by developing a non-invasive benchtop tool for single-cell metabolic analysis, enhancing understanding of diseases and treatment responses.
Projectdetails
Introduction
The HyperCell project merges two groundbreaking technologies to validate a benchtop tool for cell metabolic analysis, promising to revolutionize cell research. It empowers researchers to explore individual cell metabolic profiles, unveiling hidden disease mechanisms, understanding organism development, and revealing treatment responses. This innovation fills a crucial gap in the field, as current methods struggle to provide reliable metabolic data at the micro to picolitre scale.
Unique Features
HyperCell's standout feature is its non-invasive approach to deliver quantitative metabolic information at the single-cell level without disrupting cell metabolism. This unique capability positions ANNAIDA and NVISION as global leaders in NMR technology, offering an unmatched solution in the market.
Application Focus
The initial application for this technology is embryo analysis, addressing infertility, a widespread issue affecting one in six couples globally.
Project Goals
The project will focus on the following objectives:
- Optimization of NVISION's Quantum-Based Platform.
- Integration of technologies to enhance NMR spectrometers' sensitivity to metabolites via hyperpolarization.
- Validation of the system to enable real-time monitoring of intracellular metabolic activity.
- Utilization of ANNAIDA’s Embryospin Sensor Technology tailored for microscale NMR.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 1.998.750 |
| Totale projectbegroting | € 1.998.750 |
Tijdlijn
| Startdatum | 1-4-2024 |
| Einddatum | 30-9-2026 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- NVISION IMAGING TECHNOLOGIES GMBHpenvoerder
- ANNAIDA TECHNOLOGIES SA
Land(en)
Vergelijkbare projecten binnen EIC Transition
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Hyperpolarized NMR made simpleMAGSENSE aims to enhance NMR sensitivity by using standard hydrogen molecules as polarization batteries, enabling ultrasensitive analysis without modifying existing equipment, thus revolutionizing various fields. | EIC Transition | € 2.451.913 | 2023 | Details |
Revolutionizing Spatial Biology with a cutting-edge Multi-Scale Imaging platformThe NanoSCAN project aims to develop the SAFe-nSCAN platform for high-resolution 3D tissue analysis, enhancing molecular profiling and advancing personalized therapies in immuno-oncology. | EIC Transition | € 2.489.162 | 2023 | Details |
MIRACLE the platform for virtual biopsies; introducing Metabolic MRI-as-a-Service for oncologic careMIRACLE aims to develop a non-invasive MRI add-on for virtual biopsies, enabling personalized cancer treatment decisions by providing structural and metabolic tumor information globally. | EIC Transition | € 2.495.127 | 2022 | Details |
Non-ionizing Metabolic Imaging for predicting the effect of and guiding Therapeutic InterventionsMITI aims to develop advanced non-invasive metabolic imaging technology for early disease detection and therapy effectiveness assessment, improving patient outcomes and reducing healthcare costs. | EIC Transition | € 2.100.238 | 2022 | Details |
Early detection of treatment response in breast cancerThe project aims to enhance breast cancer treatment through Hyperpolarized Magnetic Resonance imaging for early detection of non-responders, improving outcomes and reducing side effects. | EIC Transition | € 2.499.229 | 2024 | Details |
Hyperpolarized NMR made simple
MAGSENSE aims to enhance NMR sensitivity by using standard hydrogen molecules as polarization batteries, enabling ultrasensitive analysis without modifying existing equipment, thus revolutionizing various fields.
Revolutionizing Spatial Biology with a cutting-edge Multi-Scale Imaging platform
The NanoSCAN project aims to develop the SAFe-nSCAN platform for high-resolution 3D tissue analysis, enhancing molecular profiling and advancing personalized therapies in immuno-oncology.
MIRACLE the platform for virtual biopsies; introducing Metabolic MRI-as-a-Service for oncologic care
MIRACLE aims to develop a non-invasive MRI add-on for virtual biopsies, enabling personalized cancer treatment decisions by providing structural and metabolic tumor information globally.
Non-ionizing Metabolic Imaging for predicting the effect of and guiding Therapeutic Interventions
MITI aims to develop advanced non-invasive metabolic imaging technology for early disease detection and therapy effectiveness assessment, improving patient outcomes and reducing healthcare costs.
Early detection of treatment response in breast cancer
The project aims to enhance breast cancer treatment through Hyperpolarized Magnetic Resonance imaging for early detection of non-responders, improving outcomes and reducing side effects.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Hyperpolarized Magnetic Resonance at the point-of-careHYPMET aims to revolutionize personalized cancer treatment by developing a compact NMR technology for real-time monitoring of metabolic pathways and body fluid analyses using enhanced hyperpolarization methods. | ERC Starting... | € 1.499.968 | 2024 | Details |
Valorising magnetometry in cellsThis project aims to commercialize diamond magnetometry for measuring free radical generation in living cells, potentially leading to a startup focused on innovative diagnostic solutions. | ERC Proof of... | € 150.000 | 2022 | Details |
Multidimensional in vivo metabolic flux analyses: Resolving immune cells based on in vivo metabolic phenotypesThe project aims to develop a novel nutrient uptake assay for analyzing immune cell metabolism in vivo, enhancing immunotherapy design for solid tumors through detailed metabolic insights. | ERC Proof of... | € 150.000 | 2023 | Details |
Single Molecule Nuclear Magnetic Resonance Microscopy for Complex Spin SystemsThis project aims to enhance NMR sensitivity to single molecules using scanning probe microscopy, enabling groundbreaking insights in nanotechnology and impacting NMR and SPM markets. | EIC Pathfinder | € 2.994.409 | 2023 | Details |
Optical Sequencing inside Live Cells with Biointegrated NanolasersHYPERION aims to revolutionize intracellular biosensing by using plasmonic nanolasers for real-time detection of RNA, enhancing our understanding of molecular processes in living cells. | ERC Starting... | € 1.577.695 | 2022 | Details |
Hyperpolarized Magnetic Resonance at the point-of-care
HYPMET aims to revolutionize personalized cancer treatment by developing a compact NMR technology for real-time monitoring of metabolic pathways and body fluid analyses using enhanced hyperpolarization methods.
Valorising magnetometry in cells
This project aims to commercialize diamond magnetometry for measuring free radical generation in living cells, potentially leading to a startup focused on innovative diagnostic solutions.
Multidimensional in vivo metabolic flux analyses: Resolving immune cells based on in vivo metabolic phenotypes
The project aims to develop a novel nutrient uptake assay for analyzing immune cell metabolism in vivo, enhancing immunotherapy design for solid tumors through detailed metabolic insights.
Single Molecule Nuclear Magnetic Resonance Microscopy for Complex Spin Systems
This project aims to enhance NMR sensitivity to single molecules using scanning probe microscopy, enabling groundbreaking insights in nanotechnology and impacting NMR and SPM markets.
Optical Sequencing inside Live Cells with Biointegrated Nanolasers
HYPERION aims to revolutionize intracellular biosensing by using plasmonic nanolasers for real-time detection of RNA, enhancing our understanding of molecular processes in living cells.