The first broad-spectrum treatment against pandemic-prone flaviviral infections: Dengue, West-Nile and Zika

ATLAS aims to develop the first broad-spectrum antiviral for flavivirus infections, conducting Phase I and IIa trials for dengue to attract pharmaceutical partnerships for commercialization.

Subsidie
€ 2.499.999
2023

Projectdetails

Introduction

WHO, governments, and health institutes are urgently seeking methods to prevent future catastrophic flavivirus outbreaks affecting millions. Annually, over 40% of the global population is at risk, resulting in approximately 395 million infections, more than 25,000 deaths (mainly children), 750,000 disability-adjusted life years, and over €9 billion in direct and indirect costs.

Project Overview

As there are no effective treatments or vaccines available, ATLAS will provide a breakthrough in broad-spectrum antivirals: the first-in-class drug to combat the global health emergency of flaviviral infections.

Objectives

In the ATLAS project, Protinhi will:

  1. Finalize clinical trial-enabling studies and pharmaceutical development.
  2. Obtain proof-of-concept in humans by conducting Phase I and Phase IIa clinical trials against the most common flavivirus: dengue.

Strategic Partnerships

This will put the company in an excellent position to attract interest from pharmaceutical companies (e.g., Gilead, J&J, MSD) for a strategic partnership for late clinical development and commercialization.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 2.499.999
Totale projectbegroting€ 14.465.988

Tijdlijn

Startdatum1-3-2023
Einddatum31-8-2026
Subsidiejaar2023

Partners & Locaties

Projectpartners

  • PROTINHI BVpenvoerder

Land(en)

Netherlands

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