The first broad-spectrum treatment against pandemic-prone flaviviral infections: Dengue, West-Nile and Zika
ATLAS aims to develop the first broad-spectrum antiviral for flavivirus infections, conducting Phase I and IIa trials for dengue to attract pharmaceutical partnerships for commercialization.
Projectdetails
Introduction
WHO, governments, and health institutes are urgently seeking methods to prevent future catastrophic flavivirus outbreaks affecting millions. Annually, over 40% of the global population is at risk, resulting in approximately 395 million infections, more than 25,000 deaths (mainly children), 750,000 disability-adjusted life years, and over €9 billion in direct and indirect costs.
Project Overview
As there are no effective treatments or vaccines available, ATLAS will provide a breakthrough in broad-spectrum antivirals: the first-in-class drug to combat the global health emergency of flaviviral infections.
Objectives
In the ATLAS project, Protinhi will:
- Finalize clinical trial-enabling studies and pharmaceutical development.
- Obtain proof-of-concept in humans by conducting Phase I and Phase IIa clinical trials against the most common flavivirus: dengue.
Strategic Partnerships
This will put the company in an excellent position to attract interest from pharmaceutical companies (e.g., Gilead, J&J, MSD) for a strategic partnership for late clinical development and commercialization.
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 2.499.999 |
Totale projectbegroting | € 14.465.988 |
Tijdlijn
Startdatum | 1-3-2023 |
Einddatum | 31-8-2026 |
Subsidiejaar | 2023 |
Partners & Locaties
Projectpartners
- PROTINHI BVpenvoerder
Land(en)
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