PAH-ADVANCE: Accelerating the Clinical Path of NTP42, a disease-modifying drug that will disrupt the future treatment of cardiopulmonary diseases, including pulmonary arterial hypertension (PAH).

ATXA Therapeutics aims to advance NTP42, a novel drug for pulmonary arterial hypertension, through Phase II trials and licensing to accelerate market entry and diversify its drug portfolio.

Subsidie
€ 2.500.000
2023

Projectdetails

Introduction

ATXA Therapeutics has developed NTP42, a disruptive new drug for pulmonary arterial hypertension (PAH) and related cardiopulmonary (heart & lung) diseases. NTP42 blocks the thromboxane receptor, a target at the root cause of PAH and related diseases.

Treatment Efficacy

By treating all clinical hallmarks in both the lungs and heart, NTP42 offers a game-changing solution for PAH, leading to its rapid adoption once marketed. ATXA’s Phase I clinical trial showed that NTP42 is safe and highly efficacious in humans.

Future Plans

With EIC Blended Finance and VC co-investment, ATXA will undertake a Phase II trial on NTP42 in PAH.

  1. We will then secure a licensing deal with a pharma to accelerate NTP42 to the PAH market.
  2. Projected sales are expected to exceed $1B at 5 years post-launch, with royalty returns to ATXA.

Diversification and Growth

With the proceeds of the licensing deal, we will diversify the uses of NTP42 and pipeline drugs to treat other priority target diseases. This will also enable growth, creating over 100 full-time equivalents (FTEs) and transforming ATXA into a major European pharma with a diversified diseases and drugs portfolio.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 2.500.000
Totale projectbegroting€ 4.181.504

Tijdlijn

Startdatum1-1-2023
Einddatum31-12-2023
Subsidiejaar2023

Partners & Locaties

Projectpartners

  • ATXA THERAPEUTICS LTDpenvoerder

Land(en)

Ireland

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